Nestec S.a.

Societe Des Produits Nestle S.a.

Anne Donnet-Hughes

Eduardo Schiffrin

Clara Lucia Garcia-Rodenas

Karine Vidal

Peter Van Den Broek

Denis Breuille

Olivier Ballevre

Elizabeth Offord Cavin

Jalil Benyacoub

Stephanie Blum-Sperisen

Magali Faure

Lionel Jean Rene Bovetto

Marie-Claire Fichot

Claudia Roessle

Ferdinand Haschke

Laurent Favre

Isabelle Bureau-Franz

Marco Enrico Turini

Karl-Josef Huber-Haag

Paul-André Finot

Elizabeth Offord-Cavin

Mohamed Nabil Bosco

Dominique-Anne Granato

Denis Breuillé

Stéphanie Blum-Sperisen

Denis Breuill

A nutritional composition is proposed comprising a probiotic and milk fat globule membrane (MFGM) wherein the MFGM and the probiotics mutually potentiate their respective effects and promote complementary beneficial protective mechanisms that reflect physiological synergy. The nutritional composition can be an infant formula, infant cereals, baby food or health care nutritional product. The synergistic effect can include promoting immune maturation and/or immune education and/or reducing inflammation and/or treating or preventing disease or infections.

Infant formula with probiotics and milk fat globule membrane components

The invention relates to an infant formula comprising a source of protein in an amount of not more than 2.0 g/100 kcal, a source of lipids, a source of carbohydrate and a probiotic wherein the probiotic is present in an amount equivalent to between 10and 10cfu/g of dry formula. The invention further extends to the use of such an infant formula to modulate the immune system of a neonatal infant to promote the development in the first few weeks of the life of the infant of a beneficial intestinal microbiota comparable with that found in breast fed babies as well as to promote the maturation of the immune system of a neonatal infant in the first few weeks of life.

Infant formula with probiotics

The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonization, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.

Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria

The present invention pertains to osteoprotegerin obtainable from milk sources, in particular human and bovine milk. The present invention also relates to the use thereof for preparing an ingestible preparation and/or a pharmaceutical composition, in particular to the use of such a preparation/composition for preventing or treating disorders associated with bone metabolism and immune function.

Osteoprotegerin in milk

The present invention relates to a nutritional composition suitable for patients undergoing chemotherapy and/or radiation such as cancer patients. The composition, which may be in powder or liquid form, comprises casein and whey proteins, TGF-&#x3b2; and free glutamine.

Nutritional composition against side effects of chemotherapy or radiotherapy

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Saint-Legier, Switzerland

Anne Donnet-Hughes