Basf Se Corporation

Anne-Catrin Letzel

Michael Puhl

Martin Viertelhaus

Hartwig Schroeder

Sebastian Wloch

Peter Oedman

Jacek Malisz

Chung Huan Wong

Daniel Seibert-Ludwig

Michael Barros Gross

Emiel Jan Kappert

The present invention relates to a method for obtaining crystalline 2'-fucosyllactose from a 2&#x2032;-FL raw material, which contains 2&#x2032;-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2&#x2032;-FL, where the method comprises a)providing a solution of the 2&#x2032;-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2&#x2032;-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2&#x2032;-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).

Method for obtaining crystalline 2'-fucosyllactose

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Ludwigshafen, Germany

Anne-Catrin Letzel