Qiagen Gmbh

Annabelle Schubert

Markus Sprenger-Haussels

Martin Horlitz

Uwe Oelmüller

Ralf Wyrich

Kalle Günther

Uwe OELMÜLLER

Uwe Oelmuller

Kalle Gunther

The present invention provides methods, compositions and devices for stabilizing the extracellular nucleic acid population in a cell-containing biological sample and for stabilizing the transcriptome of contained cells.

Stabilisation of biological samples

The present invention provides methods, compositions and devices for stabilizing the extracellular nucleic acid population in a cell-containing biological sample using an apoptosis inhibitor, preferably a caspase inhibitor, a hypertonic agent and/or a compound according to formula 1 as defined in the claims.

Stabilisation and isolation of extracellular nucleic acids

Stabilization and isolation of extracellular nucleic acids

The present invention provides methods, compositions and devices for stabilizing the extracellular nucleic acid population in a cell-containing biological sample using an apoptosis inhibitor, preferably a caspase inhibitor, a hypertonic agent and/or a compound according to formula (1) as defined in the claims.

The present disclosure provides methods, compositions and devices for isolating virus particles and/or viral nucleic acids from body samples that were stabilized using a stabilizing composition comprising a formaldehyde releaser agent.

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Hilden, Germany

Annabelle Schubert