Distretto Tecnologico Sicilia Micro E Nano Sistemi S.c.a.r.l.

S.i.f.i. Societa Industria Farmaceutica Italiana S.p.a.

Sifi S.p.a.

Anna Rita Blanco

Gaetano Giammona

Salvatore Cuzzocrea

Giovanna Pitarresi

Santa Viola

Gennara Cavallaro

Patrizia Saladino

Mariano Licciardi

Grazia Maria Letizia Consoli

Emanuela Fabiola Craparo

Patrizia Guarneri

Emanuela Esposito

Clara La Marca

Irene Ceidda

Maria Luisa Bondi'

Maria Grazia Mazzone

Maria Cristina Curatolo

Salvatore Papasergi

Guiseppe Granata

Giuseppe Granata

Maria Luisa Bondi′

Irene Deidda

Clara La Marco

Valeria Moschetti

Antonino Asero

Sabrina Conoci

Maria Luisa Bondi

Massimo Spata

Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases.

Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases

The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical use in the ocular bacterial infections, more preferably in the treatment of conjunctivitis, keratitis and blepharitis.

Process for preparing of aqueous formulation for opthalmic use

Growing community of inventors

Acireale, Italy

Anna Rita Blanco