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Anna Eduardovna Berzinya

Solomon Aronovich Giller

Regina Abramovna Zhuk

Laima Avgustovna Sherinya

A process for producing N.sub.1 -(.alpha.-butyrolactone)- and N.sub.1 -(.alpha.-valerolactone)-5-substituted uracils of the formula: ##SPC1## Wherein R.sub.1 is hydrogen, methyl, a trihalomethyl or a halogen; R.sub.2 is hydrogen or an alkyl, n = 1 or 2, characterized in that a bis(trimethylsilyl)-5-substituted uracil of the formula: ##SPC2## Wherein R.sub.1 is hydrogen, methyl, a trihalomethyl or a halogen, is treated with an .alpha.-bromolactone of the formula: ##SPC3## Wherein R.sub.2 is hydrogen or an alkyl, n = 1 or 2. The reaction is conducted at a temperature ranging from 80.degree. to 160.degree.C. From the reaction mixture thus obtained there is distilled off the resulting trimethylbromosilane formed during the reaction, and the reaction mixture is treated with a lower aliphatic alcohol.

Process for producing N.sub.1 -(.alpha.-butyrolactone- and N.sub.1 (.alpha.

A process for producing N.sub.1 -(dihydroxyalkyl)-5-substituted uracils of the formula: ##SPC1## Wherein

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Anna Eduardovna Berzinya