University of California

Pfizer Corporation

Northwestern University

Ann M Czyzewski

Ronald N Zuckermann

Annelise E Barron

Michelle Dohm

Ahmad Sheikh

Nathaniel P Chongsiriwatana

Vahid Zia

James A Patch

Tyler M Miller

Lyle Brostrom

Antimicrobial peptoid compounds and related compositions as can be used against bacteria effectively and selectively.

Selective poly-N-substituted glycine antibiotics

A novel mixed salt of S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine is disclosed. The novel mixed salt, S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, may be produced to form crystals that may be arranged as generally orderly packed agglomerates, which are particularly useful in making pharmaceutical compositions. Such pharmaceutical compositions are also described, as well as methods to make crystalline S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, and methods of treating conditions characterized by an overexpression on nitric oxide from the inducible isoform of nitric oxide synthase using the S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride.

S-[2-[(1-iminoethy)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride crystalline salt

Growing community of inventors

Grayslake, IL, United States of America

Ann M Czyzewski