Cytiva Sweden Ab

Ge Healthcare Bio-sciences Ab

Resistentia Pharmaceuticals Ab

Ann-Christin Magnusson

Mats Lundgren

Cecilia Anneren

Christian Kaisermayer

Bjorn Johan Lundgren

Emmanuel Macedo

Lena Maria Sandberg

Johanna Tschop

Eva Blanck

Therese Lundstrom

Gerald Blueml

Christine Sund Lundstrom

Alexis Fuentes

The present invention relates to a method for virus propagation. More closely the invention relates to a method for animal component free propagation and production of rotavirus (RV) using recombinant trypsin.

Method for virus propagation

The present invention relates to a method and system for aseptic material transfer from a storage container to a bioreactor. More precisely the invention relates to a method and system for aseptically transferring dry material, such as microcarriers for cell cultivation, to a bioreactor, comprising transferring microcarriers from a first container housing said microcarriers to a bioreactor for cell cultivation via r transfer tubing connecting the first container to the bioreactor, wherein the transfer is accomplished with pressurized air or gas supplied to the container.

Method and system for cell cultivation

The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor. The invention enables expansion to therapeutic amounts of stem cells. The method comprises the following steps: a) addition of cells in cell culture medium and microcarriers to a plastic bag container; b) allowing the cells to adhere to the microcarriers while the container is kept substantially still; c) addition of further cell culture medium once the cells have adhered; d) culturing the cells under gentle and constant agitation; e) increase the surface area for continued culturing; and f) final harvesting of cells by an active detachment and separation step.

Method for cell expansion

The invention provides methods and materials related to expressing chimeric IgE proteins. Specifically, the invention provides nucleic acid vectors, host cells, and methods for producing chimeric IgE polypeptides.

Chimeric IgE polypeptides and host cells

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Uppsala, Sweden

Ann-Christin Magnusson