University of Colorado

Ann C Halbower

Tam Vu

Shane Transue

Phuc Tien Nguyen

Min-Hyung Choi

Anh Nguyen

Various embodiments of the disclosed technology present a structural foundation for volumetric flow reconstructions for expiratory modeling enabled through multi-modal imaging for pulmonology. In some embodiments, this integrated multi-modal system includes infrared (IR) imaging, thermal imaging of carbon dioxide (CO), depth imaging (D), and visible spectrum imaging. These multiple image modalities can be integrated into flow models of exhale behaviors enable the creation of three-dimensional volume reconstructions based on visualized COdistributions over time, formulating a four-dimensional exhale model which can be used to estimate various pulmonological traits (e.g., breathing rate, flow rate, exhale velocity, nose/mouth distribution, tidal volume estimation, and COdensity distributions). Various embodiments also enable the accurate acquisition of numerous pulmonary metrics that are then stored within distributed systems for respiratory data analytics and feature extraction through deep learning embodiments.

Non-contact breathing activity monitoring and analyzing through thermal and CO2 imaging

The present invention provides a light-weight wearable sensor that can capture electroencephalogram (EEG or brain signals), electromyography (EMG or muscle signal), and electrooculography (EOG or eye movement signal) using a pair of modified off-the-shelf earplugs. The present invention further provides a supervised non-negative matrix factorization learning algorithm to analyze and extract these signals from the mixed signal collected by the sensor. The present invention further provides an autonomous and whole-night sleep staging system utilizing the sensor's outputs.

In-ear sensing systems and methods for biological signal monitoring

The present invention provides an apparatus for the measurement and monitoring of the breathing volume of a subject. In certain embodiments, the invention further provides a method of using the apparatus to diagnose a subject as suffering from a respiratory disorder. In other embodiments, the apparatus and method can be used to monitor the breathing volume of a subject, while compensating for random body movement of the subject during the monitoring period.

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Denver, CO, United States of America

Ann C Halbower