Zonhon Biopharma Institute, Inc

Gensun Institute of Biomedicine Co., Ltd.

Anliang Wang

Jun Wang

Bruce Yong Ma

Yu Fan

Peipei Cao

Yong Ma

A DNA sequence encoding Der p1 protein having a particular base sequence is codon-optimized for theexpression system, which is conducive to expressing Der p1 in. After gene optimization and adding an activating element to increase the expression of Der p1 in molecular level, it was found that Der p1 is expressed at a higher level as compared with the prior art and has biological activity similar to the natural protein.

Variant recombinant dermatophagoides pteronyssinus type 1 allergen protein and its preparation method and application

A DNA sequence encoding Der p2 protein having a particular base sequence is codon-optimized for theexpression system, which is conducive to expressing Der p2 in. After gene optimization and adding an activating element to increase the expression of Der p2 in molecular level, it was found that Der p2 is expressed at a higher level as compared with the prior art and has biological activity similar to the natural protein.

Recombinanttype 2 allergen protein and its preparation method and application

Provided are an optimized Der f2 gene, a recombinant Der f2 protein encoded thereby, a vector comprising said gene, and astrain. Also provided are an expression method, a purification method, and an application of the recombinant Der f2 protein.

Provided are an optimized proDer f1 gene, a proDer f1 protein encoded thereby, a vector comprising said gene, and astrain. Also provided are an expression method and a purification method of the proDer f1 protein.

Recombinanttype 1 allergen protein and its preparation method and application

Described is a bispecific antibody, and a method for producing the bispecific antibody. The bispecific antibody can be used in the preparation of a drug for treating a tumor with high cell expression of CD26. The antibody specifically hinds to human CD26 and human CD3 at the same time.

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Jiangsu, China

Anliang Wang