Chinese Academy of Sciences

Chinese Academy of Medical Sciences

China Institute of Water Resources and Hydropower Research

China Yangtze Power Co., Ltd.

Anjun Deng

Jing Li

Zhihui Zhang

Zhihong Li

Hailin Qin

Lianqiu Wu

Li Song

Wenjie Wang

Tianjie Lei

Xinlei Guo

Hantao Wang

Ye Yin

Cuihua Chen

Jinqian Yu

Haijing Zhang

Huachen Song

Xiaonan Tang

Hongling Shi

Qingchao Guo

Qin Lu

Dangwei Wang

An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflammatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.

Hydrophilic berberine-type derivative and application thereof in preparing drug

Provided is a lateral water intake structure for preventing silting of bed load and floating debris, which is provided at a river bank. The lateral water intake structure includes: a diversion canal, a guiding wall structure, a shaft-shaped water intaking space, and a trash rack. The lateral water intake structure functions to prevent the floating debris from gathering at the surface of the trash rack and reduce a risk that the trash rack is damaged by water pressure and hitting of the floating debris. Meanwhile, by using a water flow in the watercourse to continuously wash the floating debris near the trash rack, maintenance costs of removing the floating debris at the trash rack manually or mechanically can be reduced.

Lateral water intake structure for preventing silting of bed load and floating debris

Disclosed are derivatives of protoberberine biological alkaloids or physiologically acceptable salts thereof produced by means of a derivative reaction of a source material of biological alkaline quaternary ammonium salts of protoberberine alkaloids, a preparation method for same and pharmaceutical uses thereof. The derivatives of protoberberine biological alkaloids or the physiologically acceptable salts thereof show activity inhibiting ulcerative colitis and can be used in the preparation of drugs for same. 

Derivatives of protoberberine biological alkaloids and use of same inhibiting ulcerative colitis

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Beijing, China

Anjun Deng