Burroughs Wellcome Co.

Anjaneyulu S Tadepalli

John D McDermed

Vincent H Chang

Kevin P Hurley

Harold S Freeman

Walker A Long

Brendan J Whittle

James W Crow

Kenneth B Klein

Anti-hypertensive tetralins

The present invention is concerned with compounds of formula (I) ##STR1## wherein R.sup.1 is hydrogen or C.sub.1-4 alkoxy;

Anti-hypertensive sulfonanilides

The present invention is concerned with methods for the prophylaxis, treatment and diagnosis of pulmonary hypertension which comprise the administrative of an effective amount of a compound of formula (I) ##STR1## wherein a is an integer of from 1 to 3; X and Y, which may be the same or different, are selected from --O-- and --CH.sub.2 --;

Method of treating pulmonary hypertension with benzidine prostaglandins

The present invention is concerned with compounds of formula (I) ##STR1## wherein R.sub.1 is hydrogen;

Antihypertensive sulfonanilides

The present invention is concerned with methods for the treatment and diagnosis of pulmonary hypertension which comprise the administration of an effective amount of a compound of formula (I) ##STR1## wherein X is hydrogen or methyl;

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Durham, NC, United States of America

Anjaneyulu S Tadepalli