Mylan Laboratories Limited

Anjaneyaraju Indukuri

Ramakoteswara Rao Jetti

Hemant Malhari Mande

Vinayak Gore

Vijaya Krishna Ravi

Neelima Bhagavatula

Dnyandeo Punde

Amit Kumar Singh

Umasankara Sastry Tummalapalli

Nagaraju Gottumukkala

Chandersingh Bohra

Mahesh Kumar Gadakar

Rajesh Joshi

Narasimha Murty Pilli

Attanti Veera Venkata Srinivasarao

Kiran Pokharkar

Veera Venkata Satya Surya Appala Gosula

Narasimha Murthy Pilli

Ravi Venkata Naga Vikas Chandra Dev

Anil Kumar Tripathi

Bommareddy Aggiramireddy

Chandrakant Chaudhri

Soumyajit Ghosh

The present disclosure relates to crystalline forms of venetoclax and process for their preparation. The present disclosure also relates to process for preparation of amorphous venetoclax.

Polymorphic forms of VENCLEXTA

The present disclosure provides novel crystalline sofosbuvir form-M3 and a process for the preparation of sofosbuvir form-M3. The crystalline sofosbuvir form-M3 disclosed herein may be useful in the formulation of pharmaceutical dosage forms.

Polymorphic forms of sofosbuvir

The present disclosure provides amorphous lumacaftor, amorphous solid dispersions of lumacaftor, crystalline lumacaftor acetic acid solvate, crystalline lumacaftor ethyl acetate solvate, and processes for the preparation thereof. The lumacaftor forms disclosed herein may be useful for the preparation of oral dosage forms for treating cystic fibrosis transmembrane conductance regulator (CFTR) mediated diseases.

Forms of lumacaftor and processes for the preparation thereof

The present disclosure provides novel crystalline forms of cabozantinib (S)-malate, designated as form-M, M, Mand Mand novel crystalline forms of cabozantinib free base, form-M, Mand Mand methods of their production. The present disclosure also provides processes for the preparation of crystalline cabozantinib (S)-malate form N-1.

Polymorphs of cabozantinib (S)-malate and cabozantinib free base

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Hyderabad Telangana, India

Anjaneyaraju Indukuri