Dsm Chemie Linz Gmbh

Dsm Fine Chemicals Austria Gmbh

Anita Lamplmayr

Peter Pochlauer

Wolfram Hendel

Christian Burger

Gerald Summer

Harald Poschko

Antonia Praus

Process for the preparation of carboxylic acid succinimidyl esters by reaction of N-hydroxysuccinimide with a carboxylic acid and a halophosphoric acid ester of the formula ##STR1## in which R.sub.1 and R.sub.2 are identical or different and are a C.sub.2 - to C.sub.6 -alkyl radical or a phenyl radical, or R.sub.1 and R.sub.2 together form a C.sub.6 -aryl radical, in the presence of a base in a diluent at a temperature of 0.degree. C. up to 100.degree. C. and isolation of the corresponding carboxylic acid succinimidyl ester.

Process for the preparation of carboxylic acid succinimidyl esters

A process for the preparation of carboxylic acid succinimidyl esters by reaction of N-hydroxysuccinimide with a carboxylic acid and a halophosphoric acid ester of the formula ##STR1## is desired, in which R.sub.1 and R.sub.2 are identical or different and are a C.sub.2 - to C.sub.6 -alkyl radical or a phenyl radical, or R.sub.1 and R.sub.2 The process is carried out in the presence of a base in a diluent at a temperature of 0.degree. C. up to 100.degree. C. with isolation of the corresponding carboxylic acid succinimidyl ester.

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Anita Lamplmayr