Monsanto Technology LLC

Scientific Protein Laboratories, LLC

Anisha Akula

Brenda A Lowe

Jyoti R Rout

Michael T Mann

David R Duncan

William L Petersen

David D Songstad

Wanggen Zhang

Joel B Wilks

Brenda Lowe

Yan Wang

Dustin Nielsen

Karla Anhalt

Carmen Fritz

Ryan Ruf

Colin Crowley

Jon Restivo

Dana Spangenberg

Kenneth S Manning

Mark Romich

Joel B  Wilks

Wanggen  Zhang

A pancreatin preparation having reduced viral infectivity includes one or more pancreatin enzymes and peracetic acid (PAA). At least one pancreatin enzyme may be derived from an animal source such as a porcine pancreas gland. In a particular embodiment, the one or more pancreatin enzymes are selected from the group consisting of lipases, proteases, and amylases.

Method for reducing or inactivating viral and microbial content in the processes for the manufacture of pancreatin

A method of producing a stably transformed corn plant in a single container is demonstrated. This method allows for the automation of the transformation process and reduces labor, material, and ergonomic costs associated with traditional plant tissue culture systems.

Methods for producing transgenic plants

Production of transformed plants is achieved by placing-inoculated explants directly onto a medium containing selective agents for suppressing growth ofand killing non-transformed explant cells.

A method for the reduction or inactivation of viral and microbial content in the manufacturing of pancreatin API is disclosed. The method includes treating animal-derived tissue with peracetic acid to reduce viral activity and bacterial load prior to processing. In particular, the method includes treating porcine pancreas glands with peracteic acid prior to extracting a pancreatin API from the treated glandular tissue.

Disclosed is a reverse-phase high-performance liquid chromatography based method for evaluating degradation pathways for panctreatin active pharmaceutical ingredients.

Method for evaluating degradation pathways for pancreatin active pharmaceutical agents

A method for determining the amount of colipase in a pancreatin active pharmaceutical ingredient sample is provided, the method being a titrimetric method with a constant pH and temperature.

Method to quantify and measure excess colipase in a pancreatin active pharmaceutical ingredient

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Madison, WI, United States of America

Anisha Akula