Abyrx, Inc.

Aniq Darr

Richard L Kronenthal

John Pacifico

Frank Do

Rao Bezwada

Marci Wirtz

David Knaack

The present invention relates to settable compositions for use in surgery. The invention also provides related compositions, including surgical kits and packages, as well as methods of making and using the settable compositions.

Settable surgical implants and their packaging

Provided herein are settable and non-settable compositions for use in surgical procedures comprising a variety of disclosed particles and optionally including previously unclotted, lyophilized, optionally crosslinked mammalian blood plasma. Also provided are related compositions, including surgical kits and packages, as well as methods of making and using the compositions.

Therapeutic putties containing additives including processed human blood plasma

Provided herein are bone hemostatic and adhesive compositions for use in surgical procedures comprising a variety of disclosed particles. Also provided are related compositions, including surgical hardware, surgical kits and packages, as well as methods of making and using the compositions.

Multi-putty bone hemostatic and adhesive compositions for use in methods of installing and securing surgical hardware in bones

The present disclosure provides methods of stabilizing surgical screws comprising the intraoperative mixing of reactive putties to yield a homogenous putty composition (HPC) into which the screw is inserted, wherein the HPC comprises a polyurethane or polyurethane urea copolymer, one or more particulate materials, and one or more additive materials.

Intraoperative uses of settable surgical compositions

The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.

Compositions and methods for hemostasis

Provided herein are bio-absorbable, settable and homogenous multi-putty bone-adhesive compositions for medical use in tissue hemostasis, surgical repair and reconstruction. Also provided are improved methods of intraoperative use of said compositions for re-approximation of adjacent bone fragments to create a restored alignment and stabilize fracture line.

The disclosure relates to polyurethane and polyureaurethane based putty compositions which harden into a fully cured solid form at room temperature and body temperature and are suitable for use as a bone cement, bone substitute, hard tissue adhesive, or bone hemostatic agent.

Multi-putty adhesive and cement compositions for tissue hemostasis, repair and reconstruction

The invention relates to a device comprising a surgical material and a support material and related methods for the application of the surgical material to a wound or surgical site using the device.

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Irvington, NY, United States of America

Aniq Darr