Council of Scientific and Industrial Research

Department of Biotechnology

Anil Kumar Gupta

Suman Preet Singh Khanuja

Mahendra Pandurang Darokar

Madan Mohan Gupta

Ram Kishor Verma

Ajit Kumar Shasany

Alok Kalra

Raj Kishori Lal

Ravi Prakash Bansal

Sushil Kumar

Sunil Kumar Chattopadhyay

Anil Kumar Singh

Sudeep Tandon

Guru Das Bagchi

Janak Raj Bahl

Dharmendra Saikia

Rajendra Singh Bhakuni

Atul Prakash Kahol

Ali Arif Naqvi

Santosh Kumar Srivastava

Arvind Singh Negi

Hari Om Misra

Mansoor Alam

Chandeshwar Nath

Ankur Garg

Samresh Dwivedi

Rakesh Behari Mathur

Anirban Pal

Bhanu Pratap Singh

Aparbal Singh

Dharani Dhar Patra

Subhash Chandra Singh

Arun Kumar Kukreja

Shilpi Paul

Saudan Singh

Moti Lal Gupta

Ram Chandra

Govind Ram

Prem Dutt Dwivedi

Janardan Singh

Suman Preet Khanuja

Chhotey Lal Nil

Tersem Lal Dhami

Neeraj Jain

Ashok Kumar Agrawal

Jagdish Ghawana

Arun Kumar Agnihotri

Shikha Gupta

Om Prakesh Dhawan

Shilpi Agarwal

Anuraddha Kumar

Deeptanjali Sahoo

Vinay Kumar Khanna

Dnyaneshwar Umrao Bawankule

Sarita Singh

Anupam Maurya

Guru Das Bagachi

Rajendra Prasad Patel

Tanpreet Kaur

The present invention relates to bioactive extracts its fractions and isolation of compound from. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D, Cholinergic (muscarinic) and Serotonergic (5HT) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-demethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and &#x3b1;-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkaloids of formula 1 and 2 from the leaves of. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions ofand in the isolated compounds &#x3b1;-yohimbine, reserpiline and in a mixture 10-demethoxyreserpiline and 11-demethoxyreserpiline in 1:1.5 ratios for treating psychosis without any extra pyramidal symptoms (EPS). 

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Processes for the simultaneous and selective growth of single walled and multiwalled carbon nanotubes in a single set of experiments are disclosed. The processes may include preparing a graphite electrode rod containing catalyst selected from Fe, Co, Ni, and a mixture thereof, acting as an anode. The process may include preparing another graphite electrode rod, each electrode having a distal and a proximal end. The process may include placing the above said two electrodes parallel to each other and their axis being substantially aligned in a chamber. The process may further include creating a DC-arc discharge inside the chamber by applying a DC-current voltage. The process may further include an cooling assembly having a cooling coil that surrounds the two electrodes. The cooling assembly may be used to maintain a temperature gradient that permits the depositing of single walled and multiwalled carbon nanotubes simultaneously in one experiment.

Process for the simultaneous and selective preparation of single-walled and multi-walled carbon nanotubes

The invention provides a simple method for isolation of calliterpenone (16&#x3b1;,17 dihydroxy-3-oxo phyllocladane), a phyllocladane diterpenoid with the plant growth regulating properties, from plant genus

Process for the isolation of calliterpenone

The present invention relates to a cultivar of'CIM-Jeevan', producing high amount of herb, phyllanthin and hypophyllanthin, wherein said cultivar is developed through &#x3b3;-irradiation of superior germplasm, the said plant produces high amount of herbage yield ranging between 1.0-1.15 kg per sqm fresh total plant herb, possesses high vegetative erect growth with a height ranging between 60 to 65 cm, produces phyllanthin ranging between 0.70-0.77% in dry herb, produces hypophyllanthin ranging between 0.32-0.37% in dry herb, and shows seed germination of about 90%.

Indian basil,belongs to the family of Lamiaceae. The essential oil of Indian basil extracted via hydro or steam distillation from the leaves or whole plants is used to flavor foods, dental and oral products, in fragrances, and in traditional rituals and medicines. Extracted essential oil has also been shown to contain biologically active constituents that are insecticidal, nematicidal, fungistatic or which have antimicrobial properties. The present invention relates to the development of an early, short duration, dwarf, high essential oil, methy chavicol and linalool yielding variety of Indian basil (). Family&#x2014;Lamiaceae) named as 'CIM-SAUMYA'. This new variety of Indian basil was developed through open pollination in the germplasm followed by half-sib progeny selection and evaluation for the yield characters of selected population for 3 years in field conditions. The new cultivar possesses better growth and vegetative growth and is able to produce higher herbage, oil and better combination of methyl chavicol and linalool yield per unit area as compared to other control genotypes.

The present invention is related to the development of a novel, distinct high herb and artemisinin yielding genotype ofobtained through systematic marker assisted breeding followed by selection of uniform population in a methodical way wherein the genotype is distinct, uniform and stably maintainable by continuous rouging of off types in the population using DNA marker at early seedling stage from nursery itself and suitable for commercial cultivation.

High artemisinin yielding artemisia plant named 'CIM-arogya'

The present invention provides plant growth-promoting activities of natural plant active constituent calliterpenone and its derivatives belonging to the group phyllocladane diterpenoids. These phytochemicals and derivatives exhibit remarkable growth promoting activities on plant roots, shoots and promote seed germination both in monocotyledonous and dicotyledonous plants. These phytomolecules possess the antagonistic activity against allelochemicals of plant growth retardant nature and hence can be used to alleviate their detrimental effects.

Use of phyllocladane diterpenoids for plant growth promotion and alleviation of growth retardant allelochemicals, and method therefor

Growing community of inventors

Uttar Pradesh, India

Anil Kumar Gupta