Acs Dobfar S.p.a.

Angelo Giovanni Cattaneo

Maurizio Zenoni

Leonardo Marsili

Mario Leone

A sterile pharmaceutical composition having as its active principles piperacillin sodium and tazobactam sodium of substantially the same density, mixed with sodium bicarbonate. The mixture is soluble in water to give injectable reconstituted solutions having high stability with time.

Injectable sterile pharmaceutical composition with piperacillin sodium and tazobactam sodium as active principles

Mixtures of at least two active principles, of which at least one is the sodium salt, are precipitated from an organic solution containing the same active principles in salified or non-salified acid form.

Injectable sterile pharmaceutical formulation containing at least two active principles

Crystalline acetonitrile solvate of cefuroxime acid, useful for preparing the antibiotic cefuroxime sodium salt.

Crystalline solvate of cefuroxime acid

A bioavailable crystalline form of cefuroxime axetil, obtained by treating known crystalline or amorphous cefuroxime axetil with water or with a water-miscible organic solvent or with a mixture thereof at a temperature of between +20.degree. C. and +100.degree. C., followed by cooling and separating the crystalline product by known methods.

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Monte Marenzo, Italy

Angelo Giovanni Cattaneo