Universidade Federal De Minas Gerais

Fundacao De Amparo a Pesquisa Do Estado De Minas Gerais-Fapemig

Angelo De Fatima

Frederico Duarte Garcia

Adriana Martins Godin

Paulo Sergio De Almeida Augusto

Valbert Nascimento Cardoso

Leonardo Da Silva Neto

Maila De Castro Lourenco Das Neve

Angelica Faleiros Da Silva Maia

Simone Odilia Antunes Fernandes

This technology relates to immune system stimulating molecules to be used in the treatment of drug addiction and abuse and their synthesis processes. These molecules have a calixarene chemical structure, preferably calix[4]arene and/or calix[8]arene, coupled to an hapten analogous to cocaine, preferably GNE and/or GNC. An anti-drug vaccine, specifically anti-cocaine, is also described using such molecules. The anti-drug vaccine can be also used to prevent fetal exposure to drugs in pregnant women who use drugs and do not wish or cannot stop their use during pregnancy.

Molecules that stimulate the immune system for treatment of drug addiction, methods of synthesis, antidrug vaccine and uses

Growing community of inventors

Belo Horizonte, Brazil

Angelo De Fatima