Claremont Biosolutions LLC

Keck Graduate Institute of Applied Life Sciences

Angelika Niemz

Bruce D Irvine

Robert Doebler

Anna Hickerson

Ryan P Talbot

Barbara Erwin

Kristina Roskos

Hsiang-Wei Lu

A disposable and inexpensive biological diagnostic cartridge for the amplification and detection of nucleic acids includes a configuration having a reaction pouch for amplification which is compressed by a flexible pump pouch for detection of the amplified reaction.

System and cartridge for efficient nucleic acid testing

Lysing may include agitating a specimen in a chamber along with a medium that includes a particulate lysing material that has an affinity for a biological material. Lysing material may include beads or other material which may be coated that facilitates binding. The medium may include a fluid with a high salt or low pH level. The biological material may be eluted by lowering a concentration of salt or increasing a pH level. Lysing materials with two or more different affinities may be employed. Heating may be used. Lysing may be performed in a flow through apparatus.

Capture and elution of bio-analytes via beads that are used to disrupt specimens

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Claremont, CA, United States of America

Angelika Niemz