Diverdrugs, S.l

Loop Therapeutics, Inc.

Angel Messeguer Peypoch

Isabel Masip Masip

Antonio Ferrer Montiel

Aldo Jorge Borroto Revuelta

Balbino Jose Alarcon Sanchez

Irene Azahara Arellano Rojo

Antonio Morreale De Leon

Esther Carrasco Romero

Merc Humet

Juanlo Catena Ruiz

Vicente Felipo Orts

Carmen Montoliu Felix

Rosa Planells Cases

Almudena Perona Requena

Jaime M Merino Fernandez

Enrique Perez Paya

Francisco Sanchez Baeza

Alejandra Moure Fernandez

Daniel Gonzalez Pinacho

Ester Monlleo Mas

Natividad Garcia Villar

N-alkylglycine trimeres, their stereoisomers, racemic mixtures and salts of formula (I) below, where R, Rand R, independent of one another, are chosen from amongst cyclopropyl, sec-butyl, 2-methoxyethyl, 3-methylbutyl, cyclohexyl, 2-(N-pyrrolidinyl)ethyl, 2-(methylcarbonylamine)ethyl, 3-(2-oxo-N-pyrrolidinyl)propyl, 2-(2-pyridyl)ethyl, 2-phenylethyl, 1-(2-tetrahydrofuryl)methyl, 2-(N-imidazolyl) ethyl, 2-(4-methoxyphenyl)ethyl, 2-(3,4-dimethoxyphenyl)ethyl, 2-(2,4-dichlorophenyl)ethyl, 2-[2-(N-methyl)pyrrolidinyl]ethyl, 2-(4-aminosulfonylphenyl)ethyl, 2-(morpholine)ethyl, 3-(N,N-diethylamine)propyl, 3,3-diphenyipropyl, 3-(N,N-dimethylamine)propyl, and 2-(N,N-diethylamine)ethyl, their stereoisomeric forms and their mixtures, which are capable of blocking L-glutamate receptors and are useful for treating disorders mediated by neurodegeneration, for example, cerebral ischemia, cerebrovascular accident, migraine, depression, Huntington, Parkinson, Alzheimer, senile dementia, epilepsy and multiple and amyotrophic sclerosis.

N-alkylglycine trimeres capable of protecting neurons against excitotoxic aggressions and compositions containing such trimeres

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Barcelona, Spain

Angel Messeguer Peypoch