Mirus Corporation

St. Jude Medical Luxembourg Holdings Ii S.a.r.l. (“Sjm Lux 11”)

Tc1 LLC

Cardiomems, Inc.

St. Jude Medical Luxembourg Holdings Ii S.a.r.l. (“Sjm Lux Ii”)

St. Jude Medical Luxembourg Holdings Ii S.a.r.l.

Angad Singh

Florent Cros

Jin Woo Park

Michael Fonseca

Matthew Abercrombie

David O'Brien

Jay Yadav

Philip Matthew Fitzsimons

Yasser Boumenir

David O'brien

Systems and methods for ultrasonically-assisted placement of orthopedic implants is described herein. An example method may comprise delivering ultrasonic energy to a surgical instrument such as a screw driver, Jamshidi needle, awl, probe, or tap that is in contact with the bone region targeted for removal and/or being prepared for implant placement. The method may further comprise delivering the ultrasonic energy via a probe passed through a cannulated surgical instrument and/or implant. An example system may comprise an ultrasonic generator coupled to a transducer, a probe or surgical instrument coupled to the transducer, a cannulated surgical instrument that allows passage of the probe, and a computing device configured to control the ultrasonic generator and take input from the user.

Systems and methods for ultrasonically-assisted placement of orthopedic implants

A system and method are provided for determining a pressure associated with a lumen of a body. A wireless sensor is positioned in the lumen of the body. The sensor comprises an LC resonant circuit having a resonant frequency configured to vary in response to changes in pressure in the lumen. One or more sensor calibration parameters are stored at an external base unit. The external based unit generates and transmits an energizing signal. A ring down response is received from the wireless sensor. The system and method determine the resonant frequency of the LC resonant circuit from the ring down response and calculate the pressure in the lumen from the resonant frequency of the LC resonant circuit utilizing the one or more sensor calibration parameters associated with the LC resonant circuit.

System and method for calculating a lumen pressure utilizing sensor calibration parameters

An implantable wireless sensor is provided for determining a pressure of a lumen in a body. The sensor comprises a sensor body comprising a plurality of substrates, at least a portion of the substrates comprising a first dielectric material. An LC resonant circuit is contained with the sensor body. A capacitance of the LC resonant circuit is configured to vary in response to changes in pressure in the lumen. A first anchoring element is coupled to a proximal end of the sensor body and a second anchoring element is coupled to a distal end of the sensor body. The first and second anchoring elements are configured to lodge the sensor body within the lumen. A second dielectric material, different than the first dielectric material, is provided over at least a portion of at least one of the plurality of substrates.

Implantable wireless pressure sensor

Systems and methods for estimating anatomic alignment between two or more bones are described herein. An example method can include registering an anatomic reference frame. Additionally, the method can include establishing a respective rotational relationship between each of one or more bones and an orientation sensor attached to each of the one or more bones. The method can also include receiving, from each of the orientation sensors, orientation information, and then calculating an orientation of a bone relative to the anatomic reference frame. The method can further include calculating, using the respective orientations of the bones relative to the anatomic reference frame, an anatomic alignment parameter between first and second bones.

Systems and methods for measurement of anatomic alignment

An example augmented reality (AR) system can include a frame, a lens attached to the frame, and a plurality of cameras attached to the frame. The cameras can be configured to record a real-time image. Optionally, the real-time image can include a portion of a subject's body and/or one or more surgical instruments. Additionally, the AR system can include a plurality of inertial measurement units, where a respective inertial measurement unit is attached to each respective camera. Optionally, the AR system can be configured to display image data (e.g., medical image data) registered and superimposed on the real-time image as seen by the user of the AR system.

Augmented visualization during surgery

A system and method are provided to deploy an implant assembly in a vessel. The implant assembly comprises a pressure sensor having a body, and first and second anchoring members coupled to the body of the pressure sensor. A delivery apparatus comprises a shaft having proximal and distal ends, the shaft including a main lumen and a secondary lumen, the main lumen extending along at least a portion of the shaft. The secondary lumen extends along at least a portion of the length of the shaft, the secondary lumen joined with first and second ports provided in a sidewall of the shaft. A tether wire is configured to be slidably positioned within the secondary lumen, the tether wire having a distal portion configured to secure the implant assembly against the sidewall.

System for deploying an implant assembly in a vessel

A method and system are provided for determining a pressure associated with a lumen of a patient. A wireless sensor is positioned in the lumen of the patient. The sensor has a body with a pressure sensitive surface, including a sealed cavity that holds an inductive-capacitive (LC) resonant circuit. A capacitance of the LC resonant circuit is configured to vary in response to changes in pressure in the lumen. The LC resonant circuit has a charge time related to a quality factor (Q) of the LC resonant circuit. The LC resonant circuit is energized with an energizing signal during a measurement cycle. The energizing signal has a duty cycle with an on-time that is set, in part, based on the charge time. A ring down response is received from the wireless sensor. The ring down response is utilized to calculate the pressure associated with the lumen of the patient.

Method and system for determining a lumen pressure

An implantable wireless sensor is provided that comprises a plurality of substrates joined together to form a body with a hermetically sealed cavity therein. A capacitor (C) is provided within the cavity. A first capacitor plate is formed on an internal surface of the first substrate. An inductor (L) is provided within the cavity and coupled to form an LC resonant circuit. At least a portion of the first substrate comprises a deflectable region mechanically coupled to the first capacitor plate. The deflectable region is configured to deflect in response to changes in pressure in the artery altering a spacing between the capacitor plates and altering a resonant frequency of the LC resonant circuit. First and second anchoring elements are coupled to the body and include flexible wire loops configured to extend outward from the body to lodge within a lumen of the artery.

Wireless sensor for measuring pressure

A pressure sensor is provided that comprises an upper wafer formed from a dielectric material, the upper wafer having channels. The upper wafer includes a first capacitor plate and a second capacitor plate formed on a lower surface of the upper wafer. An inductor is contained within the channels in the upper wafer in fixed relation to the first and second capacitor plates. A lower wafer is formed from the dielectric material. A third capacitor plate is formed on an inner surface of the lower wafer. The upper and lower wafers are fused together to form a monolithic housing such that the first and second capacitor plates are arranged in parallel, spaced-apart relation from the third capacitor plate. The lower wafer comprising a pressure sensitive deflective region underlying the third capacitor plate. The deflective region deflects in response to changes in ambient pressure in the medium.

A system and method is provided for estimating orientation and position of surgical instrumentation or tools relative to a patient's bone structure. The system and/or method may include registering an axis and/or plane associated with a patient's bone. The system and/or method may further include receiving, from magnetic and orientation sensors, information indicative of orientation and position of the surgical instrument or tool relative to the registered axis and/or plane.

Systems and methods for placement of surgical instrumentation

A method of manufacturing a sensor for in vivo applications includes the steps of providing two wafers of an electrically insulating material. A recess is formed in the first wafer, and a capacitor plate is formed in the recess of the first wafer. A second capacitor plate is formed in a corresponding region of the second wafer, and the two wafers are affixed to one another such that the first and second capacitor plates are arranged in parallel, spaced-apart relation.

Method of manufacturing implantable wireless sensor for pressure measurement

A knee balancing system for measuring performance parameters associated with an orthopedic articular joint comprises a force sensing module and one or more inertial measurement units. The force sensing module comprises a housing that includes an articular surface having a medial portion and a lateral portion, each of which is substantially mechanically isolated from the other. The force sensing module also includes first and second sets of sensors disposed within the housing. The first set of sensors is mechanically coupled to the medial portion of the articular surface and configured to detect information indicative of a first force incident upon the medial portion of the articular surface. The second set of sensors is mechanically coupled to the lateral portion of the articular surface and configured to detect information indicative of a second force incident upon a lateral portion of the articular surface. The inertial measurement unit is configured to detect information indicative of an orientation of at least one of a first bone and a second bone of a knee joint.

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Marietta, GA, United States of America

Angad Singh