Jiangsu Hengrui Medicine Company Ltd.

Shanghai Hengrui Pharmaceutical Co., Ltd.

Shanghai Shenli Technology Co., Ltd.

Ang Li

Lianshan Zhang

Wei Dai

Fanglong Yang

Yali Wang

He Zhang

Jindong Liang

Xiaohui Li

Xiaolei Zhang

Jingjian Zhang

Jinjian Zhang

Quanquan Gan

Yongzhan Wang

Yichong Zhang

Xiaojing Chen

A roller embossing method for flexible graphite polar plates of fuel cells comprises: (1) adjusting a clearance of an embossing roller pair of a roller press to a target thickness value of a monopolar plate; (2) feeding a flexible graphite slab in front of the embossing roller pair, and entangling the flexible graphite slab by means of opposite rotation of the embossing roller pair; (3) after the slab is entangled, continuing to forward roll the slab for 10-100 mm, and then reversely rolling the slab for 5-90 mm by means of synchronous and opposite rotation of an upper and a lower embossing roller, wherein one time of forward rolling and one time of reverse rolling are referred to as reciprocal rolling; (4) forming a polar plate after several times of reciprocal rolling, and separating the polar plate from the embossing rollers; (5) performing subsequent treatment on the roll-formed flexible graphite polar plate.

Roller embossing method for flexible graphite polar plates of fuel cells

Ligand-cytotoxic drug conjugates, pharmaceutical compositions, preparation methods, and pharmaceutical uses thereof are provided. More specifically, a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D)is provided. The ligand-cytotoxic drug conjugate can be used to treat cancer via receptor modulation.

Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof

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Shanghai, China

Ang Li