Technion Research & Development Foundation Limited

Blirt S.a.

Andrzej Skladanowski

Yehuda G Assaraf

Hubert Van Den Bergh

Arjan Willem Griffioen

Yamit Adar Turgeman

Henk Verheul

Kristy Gotink

Patrycja Nowak-Sliwinska

Edward Borowski

Malgorzata Wysocka

Slawomir Milewski

Natalia Salewska

Maria Milewska

Joanna Boros-Majewska

Izabela Chabowska

Eran E Bram

Adam Treder

Yamit Bney-Moshe

Ewa Sadowska

The invention provides semisynthetic derivatives of Nystatin A, water soluble salts and complexes, pharmaceutical compositions and plant protection products comprising the derivatives and their use, as antifungal antibiotics (Formula 1a). 

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Hydrophobic weak base compounds such as hydrophobic weak base chemotherapeutic agents (which are not an anthracycline) for use in the treatment of medical conditions such as proliferative disease or disorder in a subject, in combination with illumination of a region in a body of the subject which is characterized by the presence of proliferating cells, are disclosed. The hydrophobic weak base compound and a wavelength of illumination are selected such that the hydrophobic weak base compound acts as a therapeutically effective photosensitizer when exposed to the illumination.

Treatment utilizing hydrophobic weak bases chemotherapeutic agents and illumination

The present invention provides IA derivative compounds of the formula: where the variables are described herein.

Imidazoacridinone derivative compounds and methods for their use

Growing community of inventors

Gdansk, Poland

Andrzej Skladanowski