Instytut Immunologii I Terapii Doswiadczalnej Pan

Instytut Immunologii I Terapii Doswiadzalnej Pan

Narodowy Instytut Lekow

Instytut Biochemii I Biofizyki Polskiej Akademii Nauk

Wojskowy Instytut Higieny I Epidemiologii

Instytut Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk

Szkola Glowna Gospodarstwa Wiejskiego W Warszawie

Andrzej Górski

Andrzej Gamian

Beata Weber-Dabrowska

Tomasz Lipiński

Ewa Zuziak

Paulina Budynek

Ryszard Miedzybrodzki

Romuald Gryko

Sylwia Parasion

Magdalena Kwiatek

Krystyna Dabrowska

Kamil Dabrowski

Monika Hejnowicz

Jaroslaw Kosakowski

Dariusz Izak

Jan Gawor

Robert Gromadka

Aleksandra RÓZYCKA

Tomasz Lipinski

Agnieszka Piotrowicz

The subject the present invention is a method of producing a pharmacologically stable form of purified and lyophilised bacteriophage preparations of increased stability and antibacterial activity, characterized in that phages produced from a bacterial lysate, for example by ultrafiltration on ultrafiltration membranes, containing a high molecular weight preparation of purified phages is stabilised most preferably with a probiotic extract in the presence or absence of neutral salts and/or organic solvents, lyophilised, characterised via HPLC chromatography, by SDS-PAGE, and bacterial lysis biological assays, and then stored under a vacuum, where the active lyophilisate is destined for phage therapy of infections and tumors.

Method of producing a pharmacologically stable form of lyophilised, active preparations of purified bacteriophages

Novel bacteriophage strains are disclosed and their use in the production of preparations for use in the treatment of bacterial infections, particularly with drug resistant strains of bacteria of the genus, particularly those belonging to the species

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Growing community of inventors

Wroclaw, Poland

Andrzej Górski