Sanofi

Sanofi-aventis

André Malanda

Yannick Evanno

Laurent Dubois

Catherine Gille

Patrick Andre Lardenois

Antonio Almario Garcia

Odile LeClerc

Luc Even

David Machnik

Christian Maloizel

Nathalie Rakotoarisoa

Danielle De Peretti

Odile Leclerc

Yannick c/o Sanofi-Aventis Département Brevets Evanno

Dubois Laurent

Compounds of formula (I): wherein R, R, R, R, R, and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

Polysubstituted 2-aryl-6-phenylimidazo[1,2-A]pyridine derivatives, and preparation and therapeutic use thereof

This disclosure relates to compounds of formula (I): wherein G, G, G, G, n, Y, Z, Z, Z, Z, and Zare as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

Derivatives of indole-2-carboxamides and of azaindole-2-carboxamides substituted with a silanyl group, preparation thereof and therapeutic use thereof

This disclosure relates to compounds of formula (I): wherein X, X, X, X, n, Y, W, and A are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

N-azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof

The disclosure relates to compounds of formula (I): wherein X, X, X, X, Z, Z, Z, Z, Ra, Rb, n, Y, and W are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof

The disclosure relates to compounds of formula (I): wherein X, X, X, X, Y, n, A, and W are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

Bicyclic derivatives of azabicyclic carboxamides, preparation thereof and therapeutic use thereof

The invention relates to compounds of the general formula (I):  Wherein X, Y, Z, Z, Z, Z, Zand n are as defined herein. The invention also relates to a method for making the same and to the use thereof in therapy.

N-(amino-heteroaryl)-1H-pyrrolopyridine-2-carboxamides derivatives preparation thereof and their use in therapy

The invention relates to compounds of formula (I): Wherein X, X, X, X, Y and W are as described herein. The invention also relates to a preparation method and to a therapeutic application.

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Paris, France

André Malanda