Morpho Detection, Inc.

Rapiscan Systems, Inc.

Science & Engineering Services, Incorporated

Analytical Detection LLC

Andrey N Vilkov

Jack A Syage

Joseph A Widjaja

Vladimir M Doroshenko

Karl A Hanold

Vadym Berkout

Joseph Adam Widjaja

Sheng-Suan Cai

Jack Albert Syage

A system includes a conductive sampling swab including a non-mesh substrate and a thermal desorber including a clamping assembly configured to releasably hold the conductive sampling swab. The clamping assembly is configured to be electrically connected to a voltage or current source, and the thermal desorber is configured to resistively heat the conductive sampling swab to a temperature sufficient to vaporize a sample material disposed on the conductive sampling swab.

Method and system for trace detection of low volatile substances

In general, a liquid phase ion mobility spectrometer is described in which ions in a drift chamber are pushed against an increasing retarding electric field by means of liquid flow. In some examples, a method comprises ionizing an analyte to generate ions; introducing the ions into a separation region of a drift chamber; directing, at a velocity, a liquid flow through the separation region to apply first forces to the ions within the separation region of the drift chamber; using an electric field with a non-zero gradient, applying second forces to the ions within a separation region of a drift chamber, the second forces counter the first forces; modifying at least one of the velocity or the electric field; and after modifying at least one of the velocity or the electric field, detecting the ions at an ion detector to generate a signal.

Liquid phase ion mobility spectrometer

The present disclosure is directed to methods and systems for detecting a chemical substance. The methods and systems include chemically modifying a sample of a substance of interest through combination with a reagent to increase the volatility of the substance of interest. The systems and methods further include performing an analysis of the substance of interest.

Temperature influenced chemical vaporization and detection of compounds having low volatility

Chemical vaporization and detection of compounds having low volatility

A dual source ionizer includes a first ionization source and a second ionization source. The first ionization source is configured to generate a first electric field. The first electric field has a first field strength that is insufficient to form NOions. The second ionization source is configured to generate a second electric field. The second electric field has a second field strength that is sufficient to form ozone and the NOions.

System and method for trace detection using dual ionization sources

The present disclosure is directed to methods and systems for detecting a chemical substance. The methods and systems include mixing a sample of a substance of interest with an additive and then producing an adduct using an ionization source. The systems and methods further include performing a spectrometric analysis of the adduct and identifying the sample using comparative spectrometric data.

Selective ion chemistry for nitrate detection

A method for detecting a chemical substance includes collecting a sample of a substance of interest and mixing the sample and at least one additive within a reaction chamber. The at least one additive includes a plurality of isotopes. The method also includes producing a plurality of adduct ions of the sample. The plurality of adduct ions has a plurality of isotopes. The method further includes performing a spectrometric analysis of the plurality of adduct ions and performing sample identification using comparative spectrometric data of the isotopes of the plurality of adduct ions.

System and method for using additives with isotopic patterns to enhance the specificity of a spectrometer

A monitor that can detect at least one molecule. The monitor includes a housing with a passage that can receive a sample, and a photocathode that is located within the housing. The monitor also includes a first ultraviolet light source that can direct ultraviolet light onto the photocathode to create electrons that ionize molecules within the sample, and a detector that is coupled to the housing to detect at least one ionized molecule. The monitor enables electron ionization (EI) of a sample for chemical analysis without the disadvantages of current methods that use a hot filament or other thermal cathode devices.

Photoemission induced electron ionization

A method for fragmentation of analyte ions for mass spectroscopy and a system for mass spectroscopy. The method produces gas-phase analyte ions, produces gas-phase odd-electron containing species separately from the analyte ions, and mixes the gas-phase analyte ions and the odd-electron containing species at substantially atmospheric pressure conditions to produce fragment ions prior to introduction into a mass spectrometer. The system includes a gas-phase analyte ion source, a gas-phase odd-electron containing species source separate from the gas-phase analyte ion source, a mixing region where the gas-phase analyte ions and the odd-electron containing species are mixed at substantially atmospheric pressure to produce fragment ions of the analyte ions, a mass spectrometer having an entrance where at least a portion of the fragment ions are introduced into a vacuum of the mass spectrometer, and a detector in the mass spectrometer which determines a mass to charge ratio analysis of the fragment ions.

Method and apparatus for ion fragmentation in mass spectrometry

A method for fragmentation of analyte ions for mass spectroscopy and a system for mass spectroscopy. The method produces gas-phase analyte ions, produces gas-phase radical species separately from the analyte ions, and mixes the gas-phase analyte ions and the radical species at substantially atmospheric pressure conditions to produce fragment ions prior to introduction into a mass spectrometer. The system includes a gas-phase analyte ion source, a gas-phase radical species source separate from the gas-phase analyte ion source, a mixing region where the gas-phase analyte ions and the radical species are mixed at substantially atmospheric pressure to produce fragment ions of the analyte ions, a mass spectrometer having an entrance where at least a portion of the fragment ions are introduced into a vacuum of the mass spectrometer, and a detector in the mass spectrometer which determines a mass to charge ratio analysis of the fragment ions.

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Aliso Viejo, CA, United States of America

Andrey N Vilkov