University of California

Andrew W Browne

William C Tang

Magdalene J Seiler

Yuntian Xue

A bioreactor device includes a solid substrate having a first face and a second face. The solid substrate at least partially defines a perfusion channel, a plurality of chambers, a fluidic inlet, and a fluidic outlet. A first sheet disposed over the first face and a second sheet disposed over the second face. Characteristically, the combination of the solid substrate, the first sheet and the second sheet define the perfusion channel and each chamber of the plurality of chambers. The plurality of chambers are arranged in rows of chambers in which adjacent chambers are positioned at opposite side of the perfusion channel. The perfusion channel extends from the fluidic inlet and the fluidic outlet having a serpentine path along each row of chambers with each chamber being in fluid communication with the perfusion channel.

3D printed micro-millifluidic bioreactors for long-term retinal organoid maintenance

Embodiments of the present systems and methods may provide imaging techniques for multidirectional imaging, light conditioning, illumination sequences, or machine learning to create algorithms created from training by other advanced imaging techniques. In an embodiment, a method for generating an image may comprise obtaining an image of an object produced by a camera and generating, from the obtained image produced by a conventional camera, using an artificial intelligence model and imaging process, an output image including additional information similar to additional information present in an image of the object produced by an advanced imaging system.

Artificial intelligence advance imaging&#x2014;processing conditioned light photography and videography to reveal features detectable by other advanced imaging and functional testing technologies

Growing community of inventors

Newport Coast, CA, United States of America

Andrew W Browne