Reprieve Cardiovascular, Inc.

Chf Solutions, Inc.

Plc Medical Systems, Inc.

Respicardia, Inc.

Gambro Uf Solutions, Inc.

Zoll Respicardia, Inc.

Cardiorenal Systems, Inc.

Andrew Victor Halpert

Mark Gelfand

Howard R Levin

John J O'Mahony

Mark Tauscher

Howard Levin

Antony Jonathan Fields

Jeffrey Testani

Robert I Rudko

Edward G Rychlick

Wieslaw Gronek

Kenneth John Luppi

Steven J Bernard

Thomas Lendway

Antonis Panteleon

Eric Conley

J Ricardo Da Silva

Jim Dillon

Sonny Behan

Per Ulrich

Zoar Engelman

J Richardo Da Silva

This present disclosure relates to fluid therapy based on adjusted urine output rate and/or sodium output rate, and associated systems, devices, and methods. Exemplary methods can include receiving a sodium excretion input for the patient; receiving a urine output rate; determining an adjusted urine output rate based on the sodium excretion input and the urine output rate; and providing fluid therapy based on the adjusted urine output rate. By determining the amount and/or rate of the infused diuretic and/or hydration fluid based on a patient's actual sodium excretion levels, embodiments of the present technology can optimize and/or customize all or a subset of a diuretic therapy to an individual patient's physiology.

Fluid therapy based on adjusted urine output rate, and associated systems, devices, and methods

Urine collection systems and associated methods and devices are disclosed herein. A representative system can include a urine collection device, a flow control assembly configured to direct a urine flow from the patient to the urine collection device, and a urine measurement device including a first sensor and a second sensor. The first sensor is configured to generate first sensor data based on a weight of the container, and the second sensor is configured to generate second sensor data based on the urine flow from the patient to the container. The system can further include non-transitory computer readable media having instructions that, when executed by one or more processors, cause the system to perform operations comprising determining a first patient urine output based on the first sensor data; and determining a second patient urine output based on the second sensor data.

Urine collection systems and associated methods and devices

A method to treat patients suffering from fluid overload including: administrating a diuretic to the patient to increase urine output of the patient; monitoring intravascular volume of the patient; and maintaining the patient in a condition in which the intravascular volume is below a baseline intravascular volume and above a hemodynamic level by adjusting the administered diuretic.

Method and system to monitor urine output and manage fluid retention in a patient

This present disclosure relates to fluid therapy based on sodium excretion, and associated systems, devices, and methods. Exemplary methods can include receiving a sodium excretion input for the patient; receiving a urine output rate; determining an adjusted urine output rate based on the sodium excretion input and the urine output rate; and providing fluid therapy based on the adjusted urine output rate. By determining the amount and/or rate of the infused diuretic and/or hydration fluid based on a patient's actual sodium excretion levels, embodiments of the present technology can optimize and/or customize all or a subset of a diuretic therapy to an individual patient's physiology.

Fluid therapy based on sodium excretion, and associated systems, devices, and methods

A apparatus and method to treat patients with acute decompensated heart failure (ADHF), heart failure or another fluid overload condition, that includes: administrating a diuretic to the patient to increase urine output of the patient; monitoring a rate or amount of urine output by the patient after administration of the diuretic; infusing a hydration liquid into the patient to induce an increase in the urine output; and adjusting the rate or amount of the hydration liquid infused into the patient to achieve a target fluid loss in the patient.

Method and system to treat acute decompensated heart failure

A method to protect kidneys of a patient undergoing cardiac surgery patient including: administrating a diuretic to the patient to increase urine output of the patient during cardiac surgery, wherein the diuretic is administered during the cardiac surgery; anesthetizing the patient with a general anesthetic during the cardiac surgery; infusing an intravenous liquid into the patient during the cardiac surgery; monitoring a rate or amount of urine output of the patient during the cardiac surgery, and automatically adjusting a rate or amount of the intravenous liquid infused into the patient to achieve or exceed a target urine output during the cardiac surgery.

Method and system to protect kidneys during surgery

A fluid replacement method including: determining the amount of urine expelled by a patient; infusing via a pump fluid from a first fluid source into a patient; determining an amount of fluid infused into the patient from the first fluid source; adjusting the operating of the pump based on the determined amount of urine expelled and the amount of fluid infused into the patient; setting a desired fluid balance for the patient; setting an amount of at least one additional fluid delivered to the patient; calculating an actual fluid balance based on the determined urine output, the determined amount of fluid infused from the first fluid source, and the set amount of said at least one additional fluid delivered; and automatically controlling the pump based on the actual fluid balance and the set desired fluid balance so the actual fluid balance conforms to the desired fluid balance.

Fluid replacement device

Devices, systems, and methods for delivering fluid therapy to a patient are disclosed herein. An exemplary method can comprise obtaining a urine output rate from a patient; causing a diuretic to be provided to the patient at a dosage rate, wherein the dosage rate is increased over a period of time such that the urine output rate increases to be above a predetermined threshold within the period of time; and causing a hydration fluid to be provided to the patient at a hydration rate. The hydration rate can be set based on the urine output rate to drive net fluid loss from the patient.

Managing fluid levels in a patient and associated devices, systems, and methods

A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.

Fluid therapy method

A system for treating disordered breathing of a human being includes an implantable transvenous stimulation lead having at least one stimulation electrode and a sensor configured to detect activity level of the human being. The system includes an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of the activity level of the human being from the sensor, wherein the circuitry is configured to cause the energy source and the pulse generator to deliver spaced apart stimulation signals to the at least one stimulation electrode while the activity level of the human being is sufficiently low to be indicative of sleep. Spaced apart stimulation pulses from the electrode are configured to extend a duration of a time of at least one breath being defined as the time from an onset of inhalation to the onset of inhalation of a successive breath.

Detecting and treating disordered breathing

An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic never through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

Growing community of inventors

Brookline, MA, United States of America

Andrew Victor Halpert