Minipumps, LLC

Wang, Bin

Urazaki, Andrew

Jiang, Fukang

Dunn, Andrew

Andrew Urazaki

Jason Shih

Fukang Jiang

Andrew Dunn

Mark Salman Humayun

Sean Caffey

Changlin Pang

William Andrew Brandt

Pedrum Minaie

Atoosa Lotfi

Didier Sagan

Gregory Harbers

Changgeng Liu

Bin Wang

Richard Purvis

Miho Matsuoka

Andres Rodriguez

Tun Min Soe

In various embodiments, a drug pump includes a housing and, within the housing, an expandable drug reservoir at least part of which is exposed to a pressurized propellant. The propellant exerts a substantially constant pressure on the drug reservoir. A flow restrictor significantly limits outflow from the pump, and preferably has both a small diameter and a long path length, which acts to control the outflow from the drug reservoir. As a result, the pump produces a substantially constant outflow.

Implantable continuous-flow pumps

Embodiments of the present invention involve a refill apparatus comprising at least one pump, a plurality of reservoirs, a plurality of reservoir fluid channels each associated with one of the reservoirs, a plurality of valves, each having a cracking pressure, for fluidically sealing the reservoir fluid channels and the outlet fluid channel, an outlet fluid channel fluidically connected to the reservoir fluid channels, and a needle having a lumen in fluid communication with the outlet fluid channel. A parameter such as a pressure level is monitored, and one or more pumps and various ones of the valves are actuated in accordance with a protocol comprising a sequence of steps whereby fluidic pathways are opened between different ones of the reservoirs and the needle in a washing and filling sequence, each of the steps being associated with an expected pressure level.

Drug refill applicator system and method of use

A removable material is deposited or otherwise applied to a flat substrate surface in a pattern corresponding to desired corrugations in a membrane, e.g., a deflection diaphragm. The applied material serves as a scaffold for a polymeric material, which is applied thereover, and following cure or hardening, the polymeric material is removed to form a finished corrugated membrane.

Method of making a corrugated deflection diaphragm

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Arcadia, CA, United States of America

Andrew Urazaki