Agilent Technologies, Inc.

Andrew S Atwell

Paul K Wolber

Eric M Leproust

Douglas A Amorese

Robert H Kincaid

Mel N Kronick

Diane Ilsley-Tyree

Methods and compositions for generating mixtures of product molecules from an initial chemical array are provided. In the subject methods, a chemical array of surface immobilized first moieties is subjected to cleavage conditions such that a composition of solution phase first moieties is produced. The resultant composition of solution phase first moieties is then contacted with one or more reactants to produce a mixture of product molecules that are different from the first moieties. Also provided are the arrays employed in the subject methods and kits for practicing the subject methods.

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Campbell, CA, United States of America

Andrew S Atwell