Lifeware Labs, LLC

Andrew Rape

Alexandros Charalambides

Brian Stancil

Carmel Majidi

Philip LeDuc

Nolen Keeys

A drug delivery device having an array of solid microneedles embedded with drugs and a light-to-heat-transducing (LTHT) element and a flexible printed circuit board containing a light source, such as a light emitting diode, which can be activated to release the drug embedded in the microneedles through localized melting. The device is worn in contact with the skin of a user, which enables the microneedles penetrate the upper layers of the user's skin. Although in contact with a user's skin, the drugs are not delivered until the device is activated. Activation can occur by an external signal received by the device or through a signal based on a physiological state of the user determined through a sensor in a closed-loop control system.

Wearable apparatus containing a digitally controlled degradeable microneedle array for intradermal drug delivery

An apparatus for communication, a system thereof, and methods of manufacture thereof are provided. The apparatus comprises a body and a printed circuit board (PCB) operatively coupled to the body. The PCB comprises a processing unit, a first communication module operatively coupled to the processing unit, and an array of assemblies. The first communication module is configured to communicate with a secondary communication module wirelessly. The array of assemblies comprises at least two rows and at least two columns. Each assembly comprises a switch and a light. The array of assemblies are operatively coupled to the processing unit. Each light is configured to change a state responsive to at least one of a change in state by the switch within the same assembly and a control signal from the first communication module.

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Pittsburgh, PA, United States of America

Andrew Rape