Cardiac Profiles, Inc.

Andrew R Lawrence

Bernhard B Sterling

Gregory I Voss

James M Perry

Rankin A Clinton, Iii

Methods, associated algorithms, and systems for determining cardiac and/or cardiovascular performance from three measurements on a subject are presented, where two of the measurements are provided by plethysmographs and one measurement is provided by an electrocardiogram. The two plethysmographs are placed different distances from the subject's heart. Certain embodiments use the three measurements to calculate intermediate variables of a left ventricular ejection time and a pre-ejection period.

Method and system for determining cardiac performance

A method for determining a cardiac function, comprising (i) determining base anatomical characteristics associated with the subject, (ii) determining pulse delay to a first body site (PD) and a second body site (PD) as a function of the anatomical characteristics, wherein the distance via the arterial tree from the aortic valve to the first body site (PD) is different than the arterial tree distance from the aortic valve to the second body site (PD), (iii) determining pulse wave velocity between the first body site and the second body site (PWV), (iv) determining pulse wave velocity between the aortic valve and the first body site (PWV) as a function of PWV, and the anatomical characteristics; and (v) determining the pre-ejection period (PEP) as a function of PDand PWV.

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Eagan, MN, United States of America

Andrew R Lawrence