Johns Hopkins University

Andrew Pieper

Solomon H Snyder

Ted M Dawson

Valina L Dawson

Richard J Traystman

Jun Bao

Mikael J Eliasson

Patricia D Hurn

Kenji Sampei

Allen S Mandir

Neutral tissue damage resulting for ischemia and reperfusion injury or neurodegenerative diseases can be prevented by administering therapeutically effective amounts of certain selective inhibitors of poly(ADP-ribose)polymerase. The inhibitors can be administered intravenously, intraperitoneally, intramuscularly, intraventricularly, or orally. They can be administered as a capsule or tablet containing single or divided dose. Alternatively, the inhibitors can be administered as a sterile solution, suspension or emulsion.

Method of using selective parp inhibitors to prevent or treat neurotoxicity

Growing community of inventors

Baltimore, MD, United States of America

Andrew Pieper