Polytherics Limited

Andrew Kyle

Antony Robert Godwin

Nicholas Evans

A conjugate comprising a protein or peptide conjugated to a therapeutic, diagnostic or labelling agent via a linker, characterised in that the linker includes at least two ˜(CH—CH—O—)˜ units within a ring, said ring being attached via a single tethering atom within the ring to the rest of the linker, or said ring being attached via two or more tethering atoms within the ring to the rest of the linker at a single point.

Conjugates and conjugating reagents comprising a linker that includes at least two (−CH2—CH2—O—) units in a ring

A conjugate comprising a protein or peptide conjugated to a therapeutic, diagnostic or labelling agent via a linker, characterised in that the linker includes at least two &#x2dc;(CH&#x2014;CH&#x2014;O&#x2014;)&#x2dc; units within a ring, said ring being attached via a single tethering atom within the ring to the rest of the linker, or said ring being attached via two or more tethering atoms within the ring to the rest of the linker at a single point.

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Cambridge, United Kingdom

Andrew Kyle