Biorez, Inc.

Theracell, Inc.

Spine Wave, Inc.

206 Ortho, Inc.

Tetrous, Inc.

Other

Conmed Corporation

Tepha, Inc.

Exogen, Inc.

Wyeth

Cordis Corporation

Cordis Corportation

Oxidor Corporation, Inc.

Andrew James Carter

Nelson L Scarborough

Bradley E Patt

Jeffrey M Ott

Mark Theodore Aronson

Bhavana Mohanraj

Kevin A Rocco

Justin Bendigo

Jacob Edward Komenda

Thomas Wilson

Keith Collins

Arthur C Watterson

Jeffrey A D'Agostino

Mark D LoGuidice

Gunnar Andersson

Ian McRury

Lawrence M Boyd

Joseph P Lane

Jared W Walkenhorst

John A Pafford

Dennis Lee

Lance M Middleton

Nikhil N Verma

Stephen H Hochschuler

Frank M Phillips

Robert Falotico

Roger J Talish

Robert S Whitehouse

Gerard H Llanos

William Robert Walsh

Robert T Potash

Ian D McRury

John J Siekierka

James William Huckle

Gregory A Kopia

Samantha Marchetti

Nikole Seil

Craig M Jones

Richard K Grant

David P Martin

Simon F Williams

Said Rizk

Werner J Blank

Tyler Lipschultz

Dennis Connelly

Charles Hegedus

Matthew Bernasconi

Sandip Agarwal

Oliver Scarborough

Nicolas J Cotton

Nicholas J Cotton

Lance Middlelton

Nikhil Verma

Ali Hussain

Arthur Watterson

Samantha Beauregard

A composition and methods of making or use thereof include a plurality of fibers forming a shape for augmenting tendon to bone repair. The physical presence of the plurality of fibers provides initial fixation, while the use of an osteoinductive material provides long term enhancement of bone formation around the site of the tendon to bone repair.

Implant compositions and methods for ligament and tendon repair

A composition for the treatment of wounds includes demineralized bone fibers (DBF) derived from allogeneic or xenogenic cortical bone and/or polymeric fibers made from resorbable and/or non-resorbable polymer, and the composition may also include an oxygen-generating material and/or an oxygen carrier.

Bone derived fibers and oxygenated wound treatments

Implant compositions and methods for surgical repair

A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

Composite scaffold for the repair, reconstruction, and regeneration of soft tissues

Demineralized bone fiber implant compositions and methods for rotator cuff and ACL repair

Compositions and methods thereof include bone fibers made from cortical bone in which a plurality of bone fibers are made into shapes that are used to augment fixation of orthopedic implants and screws. Sheets of bone fibers may be used as an interface between bone and tissue, tendons, and/or ligaments. Cylindrical shaped implants that may be placed in drilled holes in bone prior to screw placement to enhance fixation of the screw. The physical presence of the fibers provides initial fixation, while the use of an osteoinductive material provides long term enhancement of bone formation around the screw and hence fixation. The bone fiber compositions may be in the form of a cylinder or a tube. A delivery system and methods of use are also provided.

Demineralized bone fiber composition for augmentation of fixation

A composition and methods thereof include bone fibers made from cortical bone in which a plurality of bone fibers are made into shapes that are used to augment rotator cuff and acl repair. Sheets of bone fibers may be used as an interface between bone and tissue, tendons, and/or ligaments. The physical presence of the fibers provides initial fixation, while the use of an osteoinductive material provides long term enhancement of bone formation. A delivery system and methods of use are also provided.

Demineralized bone fiber composition for rotator cuff and ACL repair

A bone repair composition and methods thereof include bone fibers made from cortical bone in which a plurality of bone fibers are made into various implant shapes conducive to introduction into a patient through minimally invasive surgery. The bone fiber compositions may be in the form of a pellet or cylinder. A method includes producing the bone fiber graft efficiently with control of key parameters of cohesiveness, rehydration and swelling of the bone fiber graft. Another method includes introducing the bone fiber graft into the cannula efficiently. A method is also provided to allow introduction of a bone graft into a patient by placing the implant in a tube and expelling it through the action of a plunger.

Demineralized bone fiber composition for use in minimally invasive surgery

A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.

Implantable polymer for bone and vascular lesions

Growing community of inventors

Stow, MA, United States of America

Andrew James Carter