Biochemical Research Corporation

Other

National Foundation for Cancer Research

Andrew J Welebir

A plant growth stimulator formulation including a substantially water-soluble concentrate solution of 1-triacontanol, a polar organic solvent, metal ions having a valence of +2 or more, and other plant growth substances. Metal ions of the present invention markedly enhance the growth-stimulating effect of 1-triacontanol when applied to plant life resulting crop yield increases which may be as high as 50 to 100%. The addition of certain plant growth substances, especially auxins, alter the plants' response to the 1-triacontanol formulations containing metal ions, and broaden the effective range of concentrations of said metal ions which are effective in assisting 1-triacontanol in stimulating plant growth. In some cases, an additional synergistic effect is observed. The formulations are effective on all plant life tested, including field corn, soybeans, wheat and grains, vegetables, and other plant life. In addition, additive effects are noted in successive generations of plant life to which the formulations are applied.

1-Triacontanol plant growth stimulator formulations

A plant growth stimulator formulation including a substantially water-soluble concentrate solution of 1-triacontanol, a polar organic solvent, and metal ions having a valence of +2 or more. Metal ions disclosed in the present invention markedly increase the growth-stimulating effect of 1-triacontanol when applied to plant life resulting in crop yield increases which may be as high as 50 to 100% over controls. The formulations are effective on all plant life tested, including field corn, soybeans, wheat and grains, vegetables, and other plant life. In addition, additive effects are noted in successive generations of plant life to which the formulations are applied.

Novel condensation products between enediol ketolactones such as 5,6-0-isopropylidene ascorbic acid and 2-chloroethyl isocyanates are shown to have potent antitumor activity probably without the release of alkylating agents in vivo. While the structures of the products are not readily elucidated, activity is found to exceed that of BCNU (bis-(2-chloroethyl)-N-nitrosourea) and parallel that of the toxic and highly effective nitrosourea, MeCCNU (1-(4-trans-methylcyclohexyl)-3-(2-chloroethyl)-3-nitrosourea). Preferred compounds are condensation products of ##STR1## wherein R.sub.2 and R.sub.3 are a lower alkyl group containing 1 to 3 carbon atoms or H and

5,6,-0-Isoalkylidene ascorbic acid derivatives

A plant growth stimulator formulation including a substantially water-soluble concentrate solution of 1-triacontanol, a polar organic solvent, metal ions, and other plant growth substances. Metal ions disclosed in the present invention markedly increase the growth-stimulating effect of 1-triacontanol when applied to plant life resulting in crop yield increases which may be as high as 50 to 100%. The addition of certain plant growth substances such as auxins, gibberellins, cytokinins and kinins, and brassins and brassinosteroids alter the plants' response to 1-triacontanol formulations containing metal ions, and broaden the range at which said metal ions are effective in assisting 1-triacontanol in stimulating plant growth.

A plant growth stimulator formulation including a substantially water soluble concentrate solution of 1-triacontanol, a polar organic solvent and metal ions.

The process for the preparation of long-chain carboxylic acids which can be readily converted to alcohols. Shorter chain acids are converted to the acid chloride which may be further purified. The acid chloride is mixed with an enamine and a hindered tertiary amine in an organic solvent and then acidified to form the beta-diketone after washing the organic phase and removal of the solvent. The beta-diketone is reacted with an inorganic hydroxide or alkali metal alkoxide and acidified to produce the keto acid which can be readily converted to the respective aliphatic acid and alcohol.

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Falls Church, VA, United States of America

Andrew J Welebir