Healionics Corporation

Istar Medical Sa

Andrew J Marshall

Max Maginness

Michel Alvarez

Brandt Scanlan

Adrienne Oda

Michael J Connolly

Chad MacDonald

Christine L Glaister

Max G Maginness

This disclosure provides prosthetic arteriovenous grafts having a blood-contacting layer; an intermediate layer; and a tissue-interface layer formed of a microporous biomaterial with a textured microporous surface, the prosthetic arteriovenous grafts providing vascular access for hemodialysis and being capable of reducing perigraft fibrotic capsular formation, and a method of maintaining the patency of the prosthetic arteriovenous grafts.

Vascular grafts and method for preserving patency of the same

This disclosure provides a method for reducing or preventing the formation and/or accumulation of drusen in an eye of a mammalian subject in need thereof, the method comprising implanting one or more microporous devices into the eye, each device having a device body and an outer surface, wherein the microporous device is formed of a biocompatible elastomeric material and comprises a plurality of interconnected pores throughout the device body.

Injectable porous device for treatment of dry and wet age-related macular degeneration or diabetic retinopathy

Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis.

Corrugated microporous tissue interface for improved performance and infection resistance of vascular grafts and other implantable devices

Described herein is a device for glaucoma treatment and monitoring that comprises a combination of an intraocular pressure (IOP) sensor and a glaucoma drainage device. The device comprises an IOP sensor and an inductive antenna mounted within a porous biocompatible material that forms the drainage path. The IOP sensor is mounted in a footplate portion of the device and is mountable in the anterior chamber of an eye. The footplate portion is connected to a body portion that houses the spiral antenna by a neck portion which retains the footplate portion in a suitable position within the anterior chamber. Due to its size, the footplate portion housing the IOP sensor can readily be inserted into the anterior chamber with the body portion housing the spiral antenna located outside of the anterior chamber in a sub-scleral space to disperse the aqueous humour.

Device and method for glaucoma management and treatment

The disclosure provides granular forms of porous biomaterials and methods for forming and applying these biomaterials, including uses to promote vascularization and tissue ingrowth.

Granules of porous biocompatible materials

This disclosure provides implantable devices coated with microporous surface layers with macrotopographic features that improve bio-integration at the interface of the implantable devices and the surrounding tissue.

Growing community of inventors

Seattle, WA, United States of America

Andrew J Marshall