Valois Sas

Aptar France Sas

Btg International Limited

Optinose As

Andrew Gordon Pocock

Paul Greenhalgh

Wayne O'Hara

Stuart Brian William Kay

Stuart Kay

Xavier Donnette

Christopher John Hurlstone

Martin Joseph Murphy

Per Gisle Djupesland

Anthony David Harman

Brendan Hogan

Julian Richard Dixon

David Dakin Iowerth Wright

Jam Wilem Marinus Mijers

Julina Richard Dixon

Jam Willem Marinus Mijers

Jan Willem Mijers

David Dakin Wright

Stuart Brian Kay

Syringe for dispensing foam having a syringe barrel, a nozzle and a bore to receive a syringe plunger having a front end and a back end. The syringe plunger includes at the front end thereof a waste container defined by a cylindrical side wall, a front end wall and a rear end wall, the walls being arranged such that an external cylindrical surface of the walls forms a seal with an internal surface of the syringe barrel. The waste container has an inlet aperture in the front end wall which is in communication with the syringe nozzle when the plunger is fully depressed into the syringe barrel. The waste container further has a hydrophobic vent in the rear end wall thereof which allows air to escape from the waste container while substantially preventing foam from escaping the waste container when the syringe is in use.

Apparatus for delivering foam

A breath-actuated delivery device includes a mouthpiece through which a subject in use exhales, an air channel which is in fluid communication with the mouthpiece, and a flexible diaphragm which is disposed in the air channel. The diaphragm provides for at least a restricted air flow through the air channel until a predeterminable actuation pressure is developed in the mouthpiece, and, on generation of the predeterminable actuation pressure in the mouthpiece, provides for an air flow through the air channel.

Delivery devices

A fluid dispenser device including a body () with a dispenser orifice (), a plurality of reservoirs () on a strip () that includes a leading end () and a trailing end (), a reservoir-opening mechanism () adapted to open a respective reservoir upon actuation, and a drive mechanism () for the strip () and bring a reservoir into register with the opening mechanism. A movable wall () separates a storage housing () for the elongate strip () from a reception housing (), the elongate strip () disposed mainly in the storage housing () before the device is used and displaced progressively in the reception housing () during use. The movable wall () causes the volume of the storage housing () to decrease progressively, and the volume of the reception housing () to increase progressively.

Fluid product dispensing device

An inhaler comprising: at least one cover element () that is movable between a closed position and an open position; individual reservoirs formed on a reservoir substrate; movable support means () that are displaceable between a non-dispensing position and a dispensing position; reservoir opening means () for opening a respective reservoir in the dispensing position; loading means () for urging said movable support means towards said dispensing position; blocking means () for retaining said movable support means in the non-dispensing position; and trigger means () for releasing said blocking means; said loading means including an elastically-deformable loading element () that co-operates with a cam surface () that is connected to said at least one movable cover element; and said cam surface comprising a first portion that is adapted to load said loading means, and a second portion that co-operates with said loaded loading means.

Fluid-product dispensing device

An inhaler comprising: at least one cover element (); individual reservoirs formed on a substrate; support means () that are movable between a non-dispensing position and a dispensing position; reservoir-opening means (); displacement means () for displacing said reservoir substrate in a first direction, said reservoir substrate also being displaceable between said non-dispensing position and said dispensing position in which said opening means open a respective reservoir; loading means () for urging said movable support means towards said dispensing position; blocking means () for retaining said movable support means in the non-dispensing position; trigger means () that are actuated by inhalation; and connection means () for displacing said reservoir substrate in said first direction when said at least one cover element is displaced, said connection means being activated while said movable support means are being displaced towards said dispensing position while the user is inhaling, and being deactivated in the absence of any inhalation.

An inhaler comprising: a body; at least one cover element that is movable between a closed position and an open position; individual reservoirs formed on a reservoir substrate; movable support means that receive said reservoir substrate and that are displaceable between a non-dispensing position and a dispensing position; and an indicator device for indicating doses that have been dispensed or that remain to be dispensed, said indicator device comprising: a rotary indicator element that supports indicator means, such as numbers, colors, and/or symbols; and an actuator that co-operates with said movable support means so as to cause said rotary indicator element to turn when said movable support means return from the dispensing position to the non-dispensing position.

A mouthpiece () for a fluid dispenser device, said mouthpiece comprising a body () that is provided with a fluid dispenser orifice () through which the fluid is expelled, and said mouthpiece being characterized in that said body () presents a substantially convex elongate shape, with a top surface () incorporating said dispenser orifice () and extending longitudinally on two sides of said dispenser orifice (), two lateral bearing surfaces () being provided laterally on two sides of said dispenser orifice () for receiving the lips of the user during inhalation, said top surface () being slightly convex and said lateral bearing surfaces () being slightly concave.

Mouthpiece for a device for dispensing a fluid product

A foam transfer device is described, for use with aerosol canister apparatus for producing a sclerosant foam for the treatment of, inter alia, varicose veins. The device enables diversion of an initial quantity of below-specification foam from the canister to waste, e.g. to an integral waste chamber, before dispensing a further quantity of foam for use in treatment. The switching of the flow from the waste chamber to a different outlet for use is accomplished without interrupting the flow from the aerosol canister since this would cause the foam to drop below specification again. The waste chamber may be transparent so that the foam entering it can be observed and a decision made by a user when to stop diverting foam to waste. Alternatively, the foam may be diverted automatically e.g. when a set time has elapsed or a set volume of foam dispensed. The foam for use is normally dispensed into a syringe for subsequent injection into a varicose vein of a patient.

Apparatus and method for dispensing foam

A fluid dispenser device including at least one individual reservoir () containing a single dose of fluid, such as powder, opening means () being provided for opening an individual reservoir () each time the device is actuated, thereby enabling the user to inhale the dose contained in said open reservoir, at least 90% of the fluid contained in said open reservoir being expelled from said reservoir during inhalation.

A fluid dispenser device including at least one individual reservoir () containing a single dose of fluid, such as powder, opening means () being provided for opening an individual reservoir () each time the device is actuated, the device including a dispenser chamber () for receiving the dose of fluid contained in a reservoir () after said reservoir has been opened, an inhalation endpiece (), and an inhalation trigger system that comprises a deformable air-chamber () that co-operates with said dispenser chamber (), said dispenser chamber being displaceable between a rest position and an inhalation position, such that during inhalation through said inhalation endpiece (), said air chamber () is deformed, thereby displacing said dispenser chamber from said rest position to said inhalation position.

Fluid dispenser device

An opening device () for opening an individual reservoir () containing a single dose of fluid, such as powder, said reservoir () including a closure wall (), said opening device () comprising perforator and/or cutter means () that are adapted to cut said closure wall () of the reservoir () in such a manner that the cut portion(s) () does/do not obstruct the opening(s) () that is/are formed.

Opening device for fluid product dispensing device

Apparatus for dispensing foam for the treatment of, inter alia, varicose veins. The apparatus includes a source of foam and a dispensing device which has an inlet in communication with the source of foam, a usable foam outlet, and a waste bleed outlet. The waste bleed outlet communicates with the inlet and with the useable foam outlet, and has a higher resistance to flow of foam than that of the usable foam outlet. The useable foam outlet may be blocked off such that foam may flow through the high resistance waste bleed outlet, and the usable foam outlet may be opened such that foam may flow through the usable foam outlet.

A delivery device, in particular a breath-actuated nasal delivery device, for delivering substance, in particular one of a liquid, as a suspension or solution, or a powder containing a medicament, especially systemic or topical pharmaceuticals, or a vaccine to the nasal airway of a subject.

A fluid dispenser device including at least one individual reservoir () containing a single dose of fluid, opening means () being provided for opening an individual reservoir () each time the device is actuated, said opening means () comprising perforator and/or cutter means () and movable support means (), said movable support means () being adapted to displace an individual reservoir () against said perforator and/or cutter means () on each actuation.

Growing community of inventors

Royston, United Kingdom

Andrew Gordon Pocock