Li-cor, Inc.

I-cor, Inc.

Andrew George Ragatz

Donald Thomas Lamb

Ahmed Bouzid

Mark A Johnson

Rex A Peterson

Christopher Lesiak

Sean B Pieper

Mark Fiedler

Irma Nicholls

Filter wheel assemblies with a single actuation point to control positioning of front and rear optical filter elements simultaneously and to provide high channel density with a plurality of selectable optical filter pairs. A filter wheel assembly may include a plurality of optical filter element pairs arranged around a common axis, wherein each of the plurality of optical filter element pairs includes a first filter element and a complementary filter element, wherein each first filter element and each complementary filter element has a surface having a normal component directed toward an inner portion of the filter wheel assembly.

Compact high density rotary optical filter wheel assemblies

An imaging system that allows for unhindered access to a sample to be imaged. A housing structure is configured with a drawer having a platform. The platform may be configured to hold a sample, such as an animal, and/or the platform may be configured to mate with a sample holding member, such as a removable carrying tray for holding the sample. The drawer presents the platform to an imaging device or system internal to the housing when in a closed, or imaging, state. When in an extended state, the drawer presents the platform external to the housing to allow unobstructed manipulation of a sample on the drawer platform (or on the sample holding member on the platform). When used, a sample holding member such as a removable carrying tray may be docked with the drawer platform, and various interconnects, such as gas ports and electrical connectors, on the sample holding member engage with corresponding elements on the platform when docked. The tray may be undocked and moved to a remote location having a compatible docking station to allow for preparation or processing of a sample elsewhere. The tray may be docked with a docking station located at a sample preparation station. In the case of a live animal sample, the preparation station may include a sterile hood or other laboratory location.

Carrying tray for modular animal imaging apparatus

A fluorescence imaging system having an enclosure having an optical excitation and detection system and features designed to suppress or reduce background fluorescence. In certain aspects, all or a portion of the interior walls has a material finish and texture that provides a surface that absorbs at least a portion of any impinging excitation light and which has low auto-fluorescing properties. In certain aspects, a baffle structure is provided on the interior of the structure and is configured to mask portions of the interior and reduce the opening through which light impinges on the detector. In certain aspects, a platform having an optically transparent window is located in the interior of the housing structure for holding a sample for excitation by excitation light from an excitation source, wherein a light-trap structure is positioned or located on an opposite side of the platform relative to the excitation source and configured to receive and contain a substantial portion of any scattered or transmitted excitation light.

Optical background suppression systems and methods for fluorescence imaging

Modular animal imaging apparatus

A gas flux chamber assembly is provided that includes a lift-and-rotate mechanism and a chamber. The chamber is moved between first and second positions, wherein the chamber is positioned over a sample in the first position and is positioned outside of an area above the sample in the second position. In operation, the chamber is first lifted off of the collar and is then rotated, about a rotational axis outside of the area above the collar. These acts are reversed to move the chamber from the second position to the first position.

Gas flux system chamber design and positioning method

A gas flux chamber assembly with a soil collar and a chamber is provided. The chamber is moved between first and second positions, wherein the chamber is positioned on the soil collar in the first position and is positioned outside of an area above the soil collar in the second position. In operation, the chamber is first lifted off of the soil collar and is then rotated, about a rotational axis substantially parallel to the soil collar axis, outside of the area above the soil collar. These acts are reversed to move the chamber from the second position to the first position.

Growing community of inventors

Lincoln, NE, United States of America

Andrew George Ragatz