Centre National De La Recherche Scientifique

Andrew E Greene

Jean-Noel Denis

Arlene G Correa

Daniel Guenard

Francoise Gueritte-Voegelein

Process for the enantioselective preparation of phenylisoserine derivatives of general formula (I), in which R represents a phenyl or tert-butoxy radical, R.sub.1 represents a hydrogen atom or an alkyl radical containing 1 to 4 carbon atoms and R.sub.2 represents a hydrogen atom or a group protecting the alcohol function. ##STR1##

Process for the enantioselective preparation of phenylisosrine

Process for the enantioselective preparation of phenylisoserine

Process for preparing taxol by the condensation of a (2R, 3S) acid of general formula (I) with a taxan derivative of general formula (II), followed by the removal of the groups R.sub.2 and R.sub.3 protecting the hydroxy groups. ##STR1##

Growing community of inventors

Uriage, France

Andrew E Greene