Axon Instruments, Inc.

Fluxion Biosciences, Inc.

Andrew Blatz

Michelle Khine

Michael Schwartz

Cristian Ionescu-Zanetti

Richard R Lobdill

Apparatus and methods are provided for analysis of individual particles in a microfluidic device. The methods involve the immobilization of an array of particles in suspension and the application of experimental compounds. Such methods can also include electrophysiology studies including patch clamp recording, electroporation, or both in the same microfluidic device. The apparatus provided includes a microfluidic device coupled to a multi-well structure and an interface for controlling the flow of media within the microchannel device.

Methods and apparatus for the manipulation of particle suspensions and testing thereof

A device and a method are provided for holding a stereotactic probe in position after the probe has been precisely positioned by stereotactic procedures, such as brain surgery. The device, a stereotactic probe holder, is adjustable, as it is capable of being positioned to contact and grip a probe at a position between a stereotactic frame and a patient's head, and is suitable for holding the probe in a desired location. Methods of using the stereotactic probe holder are also provided. The invention is useful in maintaining the proper positioning of probes, such as deep brain stimulators, electrodes, cryoprobes, cannulae, and the like, after the initial placement of the probes during stereotactic surgery.

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San Mateo, CA, United States of America

Andrew Blatz