Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises”

Pharmenterprises Biotech Limited Liability Company

Andrei Yurievich Egorov

Vladimir Evgenievich Nebolsin

Boris Ferko

Artem Alexandrovich Krokhin

Yulia Romanovna Romanova

Sergei Vladimirovich Borisevich

The present invention relates to the field of medicine and virology. An attenuated influenza A virus, an influenza virus vector based thereon, and a pharmaceutical composition comprising thereof are provided, which can be used for the prevention and/or treatment of an infectious disease. In addition, the present invention relates to an attenuated influenza A virus, an influenza virus vector based thereon, and a pharmaceutical composition comprising thereof, which can be used for the treatment of oncological diseases.

Attenuated influenza vectors for the prevention and/or treatment of infectious diseases and for the treatment of oncological diseases

The invention relates to medicine and concerns a method for the prophylaxis or treatment of diseases caused by (+)RNA-containing viruses which involves the use of an effective amount of glutaryl histamine or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition for the prophylaxis or treatment of diseases caused by (+)RNA-containing viruses which contains an effective amount of glutaryl histamine or a pharmaceutically acceptable salt thereof. The present invention solves the problem of providing a novel agent which is effective in the treatment of diseases caused by (+)RNA-containing viruses of thegenus or of thegenus.

Method and agent for the treatment and prophylaxis of diseases caused by (+)RNA-containing viruses

The invention relates to medicine, in particular, to a method for preventing and/or treating a disease associated with a reduced density of interferon receptors, the method comprising administering an effective amount of glutaryl histamine or a pharmaceutically acceptable salt thereof. Said disease may be hepatitis B, herpes, papilloma virus infection, or multiple sclerosis. The invention also relates to a pharmaceutical composition for prevention and/or treatment of diseases associated with a reduced density of interferon receptors, wherein the composition comprises an effective amount of glutaryl histamine or a pharmaceutically acceptable salt thereof. The invention solves a problem of providing a novel agent effective for overcoming a resistance to interferon therapy in diseases selected from the group including hepatitis B, herpes, papilloma virus infection, or multiple sclerosis.

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St. Petersburg, Russia

Andrei Yurievich Egorov