Merck Patent Gmbh

Merck Patent Gesellschaft MIT Beschrankter Haftung

Merck Patent Gesellschaft

Merck Patent Gesellschaft MIT Beschraenkter Haftung

Andree Blaukat

Dieter Dorsch

Oliver Schadt

Frank Stieber

Melanie Schultz

Kai Schiemann

Ingo Kober

Wolfgang Staehle

Timo Heinrich

Hartmut Greiner

Maria Kordowicz

Lars Thore Burgdorf

Christina Esdar

Dirk Finsinger

Bjoern Hock

Gérard Botton

Uwe Hofmann

Tanja Henzler

Compounds selected from the group according to claimare inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumors.

Pyrimidinyl-pyridazinone derivatives for treating a disease which is influenced by inhibition of met kinase

Compounds of the formula (I) in which D, R, R, R, Rhave the meanings indicated in Claim, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumors.

Pyridazinone derivatives

Compounds of formula (I) and their uses as inhibitors of tyrosine kinases, in particular Met kinase, and their employment in methods for the treatment of tumors.

Compounds of the formula (I), in which R, R, R, Rand Rhave the meanings indicated in Claim, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.

2-(heterocyclylbenzyl)pyridazinone derivatives

Compounds selected from the group according to Claimare inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.

Pyrimidinyl pyridazinone derivatives

Compounds of the formula (I), in which R, R, R, R, R, have the meanings indicated in Claim, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.

Compounds of the formula (I), in which R, R, R, R, R' have the meanings indicated in Claim, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.

Compounds of the formula I, in which R, R, R, R, R, R, E, E', E&#x2033; and E&#x2032;&#x2033; have the meanings indicated in Claim, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.

Benzothiazolone derivatives

The invention relates to compounds of the formula (I), to the preparation and use thereof for the preparation of a medicament for the treatment of diseases, in particular tumors and/or diseases in the development or course of which kinases are involved. 

Azaheterocyclic compounds as kinase inhibitors

Compounds of the formula I in which R, R, R, R, Rhave the meanings indicated in Claim, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.

Compounds of the formula (I), in which R, R, R, D, G, Q and W have the meanings indicated in Claim (), can and be employed for the treatment of tumors.

Piperidine and piperazine derivatives

Compounds of the formula (I), in which R, R, R, D, G, Q and W have the meanings indicated in claim (), can and be employed for the treatment of tumors.

Compounds selected from the group according to claimare inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.

Compounds of the formula (I), in which Y, R, R, Rand Rhave the meanings indicated in claim, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.

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Schriesheim, Germany

Andree Blaukat