Harvard College

Andreas Volkmer

Ji-Xin Cheng

Xiaoliang Sunney Xie

Xiaoling Sunney Xie

Systems and methods are disclosed for detecting a coherent anti-Stokes Raman scattering (CARS) signal from a microscopic sample in an epi-direction. In an embodiment, the system includes at least two sources having a pump source for generating a pump field at the pump frequency, a Stoke source for generating a Stoke field at the Stoke frequency that is different from the pump frequency, optics ( ) for directing the pump and Stoke beams ( ) in a collinear fashion through a focusing lens ( ) toward a common focal spot in a sample ( ), and detector optics that images the CARS in epi-direction, which is generated by the interaction of the pump and Stoke fields ( ) with the sample ( ) and is collected by the same focusing lens ( ), towards an epi-detector ( ).

Growing community of inventors

Cambridge, MA, United States of America

Andreas Volkmer