Cytiva Sweden Ab

Ge Healthcare Bio-Sciences Ab

Andreas Torbjorn Lundin

Mats Lundkvist

Klaus Gebauer

Andreas Marcstrom

Klas Marteleur

David Gronowitz

Gustav Jose Rodrigo

Nils Norrman

Bjorn Markus Olovsson

Ronnie Palmgren

Stefan Sjolander

Bjorn A Johansson

Ola Lind

Tim Francois

Johan Fredrik Avallin

Karl Axel Jakob Liderfelt

Kerstin Elisabet Erickson

Robert Magnusson

Tuomo Valtteri Frigard

Peter Arne Reffner

Helena Nordvarg

Johan Avallin

Fredrik Lundström

Mats Nilsson

Kerstin Erickson

A multiple cavity reciprocating positive displacement pump comprising plural pump cavities each including at least one pair of one-way valves the at least one pair including an inlet valve and an outlet valve, the pump being characterised in that respective inlet valves are in fluid communication with a common inlet and respective outlet valves are in fluid communication with a common outlet. The multiple cavities may include diaphragm arranged in a radial configuration for more uniform pressure output.

Multiple cavity reciprocating positive displacement fluid pump

A flow distribution device for bioprocess systems, comprising: ⋅—a flow distribution manifold () comprising: ⋅o at least four fluid connection tubes (), wherein each fluid connection tube () comprises a first end () for fluid connection and an opposite second end () ⋅o a central common compartment () to which the second ends () of each of the fluid connection tubes () are connected, whereby the first ends () of each of the fluid connection tubes () can be in fluid communication with the central common compartment () ⋅—at least three pinching members () which are provided in connection with one fluid connection tube () of the flow distribution manifold () each, wherein each of said pinching members () can be controlled into at least a first and a second position, wherein in the first position for each of the pinching members () the pinching member pinches one of the fluid connection tubes () such that fluid flow is prevented between the first end () and the second end () of this fluid connection tube ().

Device for distributing a flow

Disclosed is a modular bio-processing unit () comprising: a housing () having one or more internal fluid paths (), the housing having at least one inlet and at least one outlet (), each in fluid communication with the fluid path or one or more of the fluid paths; one or more sensor elements () operatively associated with the or each path, said sensor(s) elements including elements of one or more of: a flow sensor, a flow rate sensor, a conductivity sensor, a pressure sensor, a pH sensor, and a light absorbance sensor such as a UV spectroscopic concentration sensor; one or more fluid flow inducing components () operatively associated with the or each fluid path; and plural valves () for preventing or reducing flow in the or each path, the housing, inlet(s), outlet(s), flow inducing component(s) and valve(s) being arranged to operate together as a bio-processing unit within or substantially within the housing.

Modular bio-processing unit and a bio-processing system employing plural units

A multiple cavity reciprocating positive displacement pump () comprises a plurality of pump cavities (), each pump cavity () including at least an inlet valve () and an outlet valve (), wherein respective inlet valves () are in fluid communication with a common inlet () and respective outlet valves () are in fluid communication with a common outlet (), and wherein the pump cavities () are arranged about a pump axis (AR) and around said common inlet () and said common outlet ().

Pumps

A separation system, a method in a separation system and an elution arrangement to be provided in a separation system for separating a biomolecule from a cell culture are provided. The method comprises the steps of: &#x2014;providing a feed from a cell culture () comprising said biomolecule to a magnetic separator () and providing to the magnetic separator magnetic beads comprising ligands capable of binding this biomolecule; &#x2014;separating by the magnetic separator said magnetic beads with bound biomolecules from the rest of the feed; &#x2014;forwarding said magnetic beads as a slurry with an added buffer to an elution cell (); &#x2014;eluting the bound biomolecules in the elution cell.

Method and system for separating biomolecules

Disclosed is a gear pump () comprising a contra rotating gear element pair (and) mounted within a housing (), each gear element having complementary gear teeth sets providing a pumping action in use, said teeth being formed from an annulus (and) of generally rigid construction mounted on a relatively flexible inner section (and), the gear pair being mounted such that their respective annuli are biased into resilient contact with the housing to provide a sliding seal.

Gear pumps

The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic or hydraulic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic or hydraulic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.

Remotely actuated valve for a biological liquid treatment system

Growing community of inventors

Uppsala, Sweden

Andreas Torbjorn Lundin