Forschungsverbund Berlin E.v.

Ludwig-Maximilians-Universitat München

Andreas Stengl

Christian Hackenberger

Heinrich Leonhardt

Dominik Schumacher

Jonas Helma-Smets

Marc André Kasper

Maria Glanz

Tom Sauer

Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene- or alkyne-phosphonamidates comprises the steps of

Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates

Disclosed are novel conjugates and processes for the preparation thereof. A process tor the preparation of alkene- or alkyne-phosphonamidates comprises the steps of (I) reacting a compound of formula (III), with an azide of formula (IV), to prepare a compound of formula (V), reacting a compound of formula (V) with a thiol-containing molecule of formula (VI), resulting in a compound of formula (VII). 

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Andreas Stengl