Johnson Matthey Public Limited Company

Andreas Seger

Antonio Zanotti-Gerosa

Alan Dyke

Walter Leitner

Frederick Ernest Hancock

Giancarlo Francio

Brian Adger

Jonathan Alan Medlock

Hans Guenter Nedden

Stephen James Roseblade

Damian Mark Grainger

Vilvanathan Sivakumar

Jacques Jean Marie Le Paih

Thomas Pullmann

Thomas Pullman

Alan Malcolm Dyke

Zanotti-Gerosa Antonio

Jacques Jean-Marie Le Paih

The present invention relates to a process for hydrogenating a substrate including a carbon-heteroatom double bond, the process including the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof.

Process for hydrogenating ketones in the presence of Ru(II) catalysts

The present invention relates to a process for hydrogenating a substrate comprising a carbon-heteroatom double bond, the process comprising the step of reacting the substrate with hydrogen gas in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst is a complex of formula (I): R, A and Hal are as defined in the specification. The present invention also provides processes for the preparation of the complex of formula (I) and intermediates thereof. 

Methods of making a chiral phosphorus compound of formula (X) are disclosed: wherein R, R, Rare chiral or achiral groups selected from the list consisting of substituted or unsubstituted straight-chain, branched-chain or cyclic aliphatic or aromatic groups and in which the pair R/Rmay be interconnected to form a ring.

Chiral phosphorus compound

The present invention relates to novel chiral phosphorus compounds which can be readily prepared from quinoline derivatives as inexpensive starting compounds and have the general formula (I) wherein R, R, R, R, Rare chiral or achiral organic residues which are derived from substituted or unsubstituted straight or branched chain or cyclic aliphatic or aromatic groups and which, in the case of the pairs R/Rand R/R, may be interconnected. Further, the invention relates to methods for the synthesis of chiral phosphorus compounds of general formula (I) and their use as catalyst components in processes for the preparation of optically active products.

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Soham, United Kingdom

Andreas Seger