Degussa Aktiengesellschaft

Georgia Tech Research Corporation

Dow Global Technolgoies LLC

Other

Rohm and Haas Company

Texaco Inc.

Florida State University Research Foundation, Inc.

Emory University

Andreas Sebastian Bommarius

Karlheinz Drauz

Stefan Verseck

Olaf Burkhardt

Hans Henniges

Andreas Karau

Jean-Louis Philippe

Hans-Peter Krimmer

Jens Woeltinger

Gaurav Agrawal

Maria-Regina Kula

Phillip Ray Gibbs

Yoshiaki Kawajiri

Bettina Bommarius

Jungmin Oh

Mark R Prausnitz

Werner Hummel

Christian Wandrey

Christopher W Jones

Rick P Trebino

Paul Edward Doll

Sudhakar Balijepalli

John Anderson Roper, Iii

Timothy Charles Frank

Josef Altenbuchner

Oliver May

Juan Jose Almena Perea

Christoph Syldatk

Ingo Klement

Matthew James Realff

Melanie Hall

Megan E Donaldson

Andreas Liese

Birgit Geueke

Prabuddha Bansal

Jay Hyung Lee

Heike Slusarczyk

Adam Holewinski

Gunther Oehme

Ronald William Rousseau

William Wellborn

Ronald W Smith

Lutz Krieg

Grant Marshall

Marion Ansorge-Schumacher

Christopher R Murdock

John M Robbins

Akihiro Nomura

Giovanni Gadda

Martin Siemann-Herzberg

Markus Werner

Jun-Ichiro Hirano

Stephan Laue

Vaijayanthi Thangavel

Balamurali Sreedhar

Jonathan Taejoo Park

Matthew Joseph Mistilis

Jens Woltinger

Mark W Kimmel

Matt Mcdonald

Colton Lagerman

Martha Anna Grover

William Christopher Edens

Bettina Riebel-Bommarius

John Anderson Roper Iii

Giovani Gadda

Bettina R Bommarius

Mark Prausnitz

Disclosed herein are devices, systems, and methods of use thereof for magnetic separation. For example, disclosed herein is a device for separation of a mixture comprising a magnetic solid and a non-magnetic solid. The device comprises a separation chamber extending from a proximal end to a distal end; the proximal end defining an inlet; the distal end defining a first outlet and a second outlet. The separation chamber having a region that is configured to subject the fluid flowing through said region to a magnetic field to thereby separate the mixture into a first portion and a second portion; the first portion being enriched with the non-magnetic solid relative to the second separated portion; and the second portion being enriched with the magnetic solid relative to the first separated portion.

Devices, systems, and methods of use thereof for magnetic separation

A coating for conversion of formaldehyde to carbon dioxide includes an alcohol/aldehyde oxidase and a formate oxidase immobilized on a solid particulate support; and a latex binder.

Coating for aldehyde remediation and method of making

Formulations and methods are provided for stabilizing antigens in dry solid vaccines. One aspect relates to dry solid formulations of influenza vaccines including one or more excipients identified as imparting stability to influenza antigens. Another aspect relates to dry solid formulations of measles vaccines including one or more excipients identified as imparting stability to a measles antigen. The formulations may be in a form suitable for reconstitution in a physiologically acceptable liquid vehicle to form an injectable solution or suspension for administration to a patient or in the form of dissolvable microneedles or coated microneedles.

Thermally stable vaccine formulations and microneedles

The present disclosure provides for a process for supplying a first reactant and a second reactant (reactants) to a simulated moving bed reactor (SMBR) at each step of a sequential repeating injection cycle, where the SMBR includes zones each having an injection point and each containing a solid separation media; reacting the reactants in the SMBR during the sequential repeating injection cycle (cycle) to form a first product; separating the first product in the SMBR with the solid separation media; and changing an amount of one or both of the reactants injected at one or more of the injection points of the SMBR during a step of the cycle. Changing the amount of the reactants can be done at each step of the sequential repeating injection cycle. Changing the amount can include changing an inlet concentration of the reactants injected at one or more of the injection points during each step of the cycle.

Process for operating a simulated moving bed reactor

A process for conducting equilibrium-limited chemical reactions that produce water as a reaction product. Specifically, a process that uses a reactive chromatography unit (RCU) to improve the efficiency of equilibrium-limited reactions, such as a process for reacting glycol ether (GE) and carboxylic acid (CA) to form water and glycol ether ester (GEE). The process includes supplying GE and CA to the RCU, where one of either the CA or the GE is in a stoichiometric deficit relative to the other reactant. The reactant in the stoichiometric deficit reacts in the presence of the catalyst in the RCU to form a mixture of GEE and water. A raffinate is separated from the mixture using the separation media of the RCU contains at least the GEE. An extract separated from the mixture using the separation media of the RCU contains at least the water.

Process for equilibrium-limited reactions

In one embodiment the instant invention generally pertains to a method for producing glucose for fermentation. The method comprises first treating a biomass with acid and heat under conditions sufficient to produce a composition mixture comprising cellulose suitable for enzymatic hydrolysis. Next, at least a portion of the cellulose of step (a) is enzymatically hydrolyzed under conditions sufficient to form a composition comprising glucose. The glucose is then fermented. Advantageously, one or more reaction conditions are more efficient because they are selected by first measuring an initial hydrolysis rate of said biomass and then selecting one or more appropriate reaction conditions based upon said initial hydrolysis rate.

Methods of enzymatic hydrolysis

The present disclosure relates generally to bacterial NADH oxidases and, more particularly, to novel NADH oxidases obtained from, and derivatives thereof that demonstrate enzymatic activity for NADH, NADPH, or both NADH and NADPH. The compositions comprising an NADH oxidase obtained fromor derivatives thereof include: isolated enzymes; recombinantly produced enzymes and derivatives thereof, as well as catalytically active portions thereof; nucleic acids encoding an NADH oxidase obtained from, derivatives thereof, and portions thereof. The methods of the present invention include isolation of NADH oxidases obtained from, derivatives thereof, and portions thereof, and methods for enzymatic reactions comprising NADH oxidase obtained from, including the production of enantiomer-enriched organic compounds.

Compositions and methods for using NADH oxidases

The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected racemic amino acids into optically pure amino acids.

Process for the production of amino acids

A new generation polarimetry apparatus and methodology is disclosed, which involve passing polarized light through a sample including a chiral analyte, where the analyte is under the influence of a periodically varying magnetic field. The apparatus also utilizes optical heterodyne detection and lock-in detection at higher order harmonics of the magnetic field modulation frequency to improve sensitivity and detection limits of optical properties of chiral analytes.

High-throughput chiral detector and methods for using same

The present invention is directed to compositions and methods comprising NAD(P)H oxidases, particularly bacterial oxidases, nucleic acids, recombinant plasmid vectors and recombinant proteins therein encoded, and host cells comprising the oxidases and nucleic acids. The present invention also comprises an isolated bacterial oxidase that oxidizes both NADH and NADPH. Methods for producing the enzymes and enzymatic reactions comprising use of NAD(P)H oxidases and products of such reactions are also disclosed.

Methods and compositions for NAD(P)(H) oxidases

Process for the racemization of N-protected amino acids using racemase

The present invention relates to an amidase enzyme, nucleic acids encoding the amidase, as well as methods of employing the nucleic acids and/or amidase to produce, for example, enantiomericallyenriched compounds such as D-amino acids.

Amidase from variovorax

The present invention relates to a new D-carbamoylase and the gene sequences which code for this from the organism DSM 20117. Plasmids, vectors, microorganisms, particular primers and specific possible uses of the enzymes according to the invention are also mentioned. The invention moreover describes a new process for the discovery of enzymes which can be employed in a process for the preparation of D-amino acids starting from 5&prime;-substituted hydantoins.

Arthrobacter D-carbamoylase and methods of preparing enantiomerically enriched D-amino acids

The invention relates to the use of the N-acetyl amino acid racemase from subspecies for the racemiszation of N-carbamoyl amino acids. This use permits the 100% preparation of optically pure amino acids starting from racemic hydantoins in an enzymatic overall process.

Acetyl amino acid racemase from amycolatopsis orientalis for racemizing carbamoyl amino acids

Use of molecular weight-enlarged catalysts in a process for asymmetric, continous hydrogenation, novel molecular weight-enlarged ligands and catalysts

Growing community of inventors

Atlanta, GA, United States of America

Andreas Sebastian Bommarius