Schering Aktiengesellschaft

Bayer Pharma Aktiengesellschaft

Genzyme Corporation

Bayer Intellectual Property Gmbh

Alcafleu Management Gmbh & Co. Kg.

Andreas Sachse

Georg Rossling

Jutta Riedl

Jens Leike

David Harris Margolin

Patricia J Sulak

The present invention relates to a flexible extended use regimen for a hormonal contraceptive useful to manage bleeding problems associated with fixed extended use of hormonal contraceptives and to a pharmaceutical package containing the respective hormonal contraceptive.

Management of breakthrough bleeding in extended hormonal contraceptive regimens

A process for increasing the stability of liposome suspensions that contain hydrophilic active ingredients is described, which is characterized in that the active ingredient that is to be encapsulated in the liposomes is metered such that 5% to 95% by weight of the active ingredient is present in unencapsulated form.

Process for increasing the stability of liposome suspensions that contain hydrophilic active ingredients

Pharmaceutical preparations are provided comprising antiandrogenically effective substances encapsulated in liposomes. These preparations are preferably used for topical treatment of androgen-dependent diseases.

Pharmaceutical preparations

A process is described for the production of aqueous dispersions involving removal of liquid(s) from an optionally multiphase liquid mixture by means of membrane distillation, e.g., transmembrane distillation or pervaporation.

Aqueous dispersion containing liposomes

Process for the preparation of aqueous dispersions

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Berlin, Germany

Andreas Sachse