Siemens Healthcare Diagnostics Products Gmbh

Andreas Rechner

Norbert F Zander

Thomas Wissel

Andreas Kappel

Joerg Endermann

Sina Stephan

The invention lies in the area of platelet function diagnostics and relates to a method for the determination of platelet function under flow conditions as well as a device for the implementation of this method. The method is particularly suitable for the determination of the effect of clopidogrel and of other P2Y(12) antagonists with antithrombotic activity as well as the determination of P2Y(1) antagonists with antithrombotic activity.

Method and device for the determination of platelet function under flow conditions

The invention lies in the field of platelet function diagnostics and relates to devices and methods for determining the platelet function in a centrifugal analyzer.

Devices for determining the platelet function in a centrifugal analyzer

The invention is in the field of coagulation diagnostics and relates to in vitro methods for determining thrombocyte function using measuring cells, particularly measuring cells of the PFA system. The methods make it possible to obtain standardized measured results which are comparable, irrespective of the type of measuring cell used.

Method for standardizing measured results in a system for measuring thrombocyte function

The invention lies in the area of platelet function diagnostics and relates to an in vitro method for the determination of platelet function under flow conditions. The method is particularly suitable for the determination of the effect of clopidogrel after oral intake and of other P2Y(12) antagonists with antithrombotic activity as well as the determination of P2Y(1) receptor antagonists with antithrombotic activity.

Method for determination of platelet function under flow conditions

A homogeneous method of determining inhibitors of proteolytically active coagulation factors (anticoagulants) in a sample, in particular direct thrombin and factor Xa inhibitors, and also a test kit to be used in such a method. Use is made of ligands which bind to the proteolytically active coagulation factor but are not cleaved by the latter and compete with the anticoagulant to be determined.

Method of determining inhibitors of coagulation

The present invention is in the field of coagulation diagnostics and relates to a kit and method for preparing controls for use in test methods for determining thrombocyte function.

Controls and kit for thrombocyte activity tests

The present invention is in the area of coagulation analysis and relates to a reagent which is based on recombinant or native tissue factor and phospholipids and which can be stabilized by adding a polyphenol.

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Marburg, Germany

Andreas Rechner